ArticleInternational urology and nephrology2026
Effect of perivascular adipose tissue on patency and maturation rate of arteriovenous fistula in hemodialysis patients.
Article in International urology and nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Comment on "Assessing the real-world safety of sparsentan for immunoglobulin A nephropathy: insights from a comprehensive analysis of FAERS database".International urology and nephrology · 2026Article
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Authors and funding
7 authors.
Funding
Abstract
purposeThis prospective observational study aimed to examine the effects of the volume of perivascular adipose tissue (PVAT) and the fat attenuation index (FAI) on maturation and primary patency following the formation of an initial arteriovenous fistula (AVF).
methodsThis study enrolled 106 patients who underwent first-time upper limb AVF creation. PVAT volume and FAI were quantified using non-contrast computed tomography (CT) within 2 weeks postoperatively. Patients were monitored for 12 months to evaluate primary patency and maturation. Statistical analyses included receiver operating characteristic (ROC) curve analysis to determine optimal cutoff values for group stratification, Kaplan-Meier survival analysis with the Log-rank tests, and multivariable Cox proportional hazards regression to identify independent risk factors.
resultsA total of 33 patients (31.1%) exhibited adverse events within 1 year. ROC analysis determined the optimal cutoffs for group stratification of 4.32 cm
conclusionsIn this prospective cohort, lower PVAT volume and higher FAI were independently associated with an increased risk of adverse events and decreased primary patency following AVF formation. According to these findings, AVF outcomes may be influenced by the perivascular adipose microenvironment, and PVAT volume and FAI may be useful imaging biomarkers for risk assessment.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.