Evidence map›Paper›PMID 41785943›Full record

ArticleJournal of pain and symptom management2026

Racial Disparities in Non-Stigmatized Supportive Care Medication Use in Pancreatic Cancer.

Olga Monika Trejos Kweyete, Chardaé Whitner, David L Deremer, Yi Guo, Jiang Bian, Lisa Scarton, Sherise C Rogers, Diana J Wilkie, Xiwei Lou, John M Allen

Abstract read
In one paragraph

Article in Journal of pain and symptom management, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Olga Monika Trejos KweyeteDepartment of Pharmacotherapy and Translational Research (O.M.T.K.), University of Florida College of Pharmacy, Orlando, Florida, USA.
Chardaé WhitnerDepartment of Pharmacy Education and Practice (C.W.), University of Florida College of Pharmacy, Jacksonville, Florida, USA.
David L DeremerDepartment of Pharmacotherapy and Translational Research (D.L.D.), University of Florida College of Pharmacy, Gainesville, Florida, USA.
Yi GuoDepartment of Health Outcomes & Biomedical Informatics (Y.G., X.L.), University of Florida College of Medicine, Gainesville, Florida, USA.
Jiang BianDepartment of Biostatistics and Health Data Science (J.B.), Indiana University School of Medicine, Indianapolis, Indiana, USA; Melvin and Bren Simon Comprehensive Cancer Center (J.B.), Indiana University, Indianapolis, Indiana, USA; Regenstrief Institute (J.B.), Indianapolis, Indiana, USA.
Lisa ScartonDepartment of Family, Community, and Health Systems Science (L.S.), University of Florida College of Nursing, Gainesville, Florida, USA.
Sherise C RogersBrown University Health Cancer Institute (S.C.R.), Providence, Rhode Island, USA.
Diana J WilkieDepartment of Biobehavioral Nursing Science (D.J.W.), University of Florida College of Nursing, Gainesville, Florida, USA.
Xiwei LouDepartment of Health Outcomes & Biomedical Informatics (Y.G., X.L.), University of Florida College of Medicine, Gainesville, Florida, USA.
John M AllenPurdue University College of Pharmacy (J.M.A.), West Lafayette, Indiana, USA. Electronic address: john.allen@purdue.edu.

Funding

Tissue Modeling & Drug Development Shared Resources CoreU54CA233444 · NCI · UNIVERSITY OF FLORIDA · PI Chanita A. Hughes-Halbert, Tianze Jiao · 2018 to 2026
$12.1M
Tissue Modeling CoreU54CA233465 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JOYCE M RICHEY · 2018 to 2026
$11.9M
Tissue Modeling CoreU54CA233396 · NCI · FLORIDA AGRICULTURAL AND MECHANICAL UNIV · PI Sandra G Suther · 2018 to 2026
$9.8M
The benefits and harms of lung cancer screening in FloridaR01CA246418 · NCI · UNIVERSITY OF FLORIDA · PI BIAN, JIANG, GUO, YI · 2020 to 2023
$1.7M
Using Electronic Health Records from a Large Clinical Data Research Network to Understand Cancer Burden and Cancer Risks Among Transgender and Gender Nonconforming (TGNC) IndividualsR21CA245858 · NCI · UNIVERSITY OF FLORIDA · PI BIAN, JIANG, GUO, YI · 2020 to 2021
$773k
Examining the determinants and consequences of supportive care medication use disparities in patients with pancreatic cancer: A sequential mixed-methods approachR01MD019684 · NIMHD · UNIVERSITY OF FLORIDA · PI ALLEN, JOHN M · 2024 to 2024
$515k
Optimizing the Population Representativeness of Older Adults in Cancer TrialsR21CA253394 · NCI · UNIVERSITY OF FLORIDA · PI BIAN, JIANG, GUO, YI · 2021 to 2021
$392k
NCI NIH HHS HHSN261201800009CNCI NIH HHS HHSN261201800009INCI NIH HHS HHSN261201800015CNCI NIH HHS HHSN261201800015INCI NIH HHS HHSN261201800032CNCI NIH HHS HHSN261201800032INCI NIH HHS R01 CA246418NCI NIH HHS R21 CA245858NCI NIH HHS R21 CA253394NCI NIH HHS U54 CA233396NCI NIH HHS U54 CA233444NCI NIH HHS U54 CA233465NIMHD NIH HHS R01 MD019684
6 · The paper itself

Abstract

backgroundPancreatic cancer (PC) is associated with a high symptom burden that contributes to reduced health-related quality of life (HRQoL) and adverse clinical outcomes. Supportive care medications (SCMs) are essential for symptom management. Prior studies have documented racial disparities in the use of stigmatized medication classes such as opioids and psychotropics. However, less is known about whether similar disparities exist for non-stigmatized SCMs. This study examined racial and ethnic differences in the use of non-stigmatized SCMs during end-of-life care among patients with PC.

methodsWe conducted a retrospective cohort study using SEER-Medicare data from 2005 to 2017. Patients with PC who had continuous Medicare Parts A, B, and D coverage and died within 12 months of diagnosis were included. SCM use was defined as at least one outpatient prescription claim for antiemetics, appetite stimulants, cognitive aids, headache aids, or sleep aids. Multivariable logistic regression models were used to estimate adjusted odds ratios (aORs) for SCM use by race and ethnicity, controlling for demographic, clinical, and socioeconomic factors.

resultsThe final cohort included 74,309 patients (Non-Hispanic White: 72.5%, Black: 11.0%, Hispanic: 9.6%, Asian/Pacific Islander: 6.6%). Compared to Non-Hispanic White patients, Black patients had lower use of antiemetics (aOR 0.77; 95% CI: 0.73-0.81), headache aids (aOR 0.68; 95% CI: 0.63-0.74), and sleep aids (aOR 0.68; 95% CI: 0.64-0.72), but higher use of appetite stimulants (aOR 1.06; 95% CI: 1.01-1.11) and cognitive aids (aOR 1.38; 95% CI: 1.25-1.53). Similar patterns were observed for other racial and ethnic minority groups, though findings varied by medication class.

conclusionRacial and ethnic disparities persist in the use of non-stigmatized SCMs among patients with PC at the end of life. These findings extend prior evidence on inequities in cancer symptom management and underscore the need for interventions that promote equitable access to SCMs across diverse populations.

Indexed as

Healthcare DisparitiesPalliative CarePancreatic NeoplasmsAgedAged, 80 and overFemaleHumansMaleMedicareRetrospective StudiesSEER ProgramTerminal CareUnited Statescachexiacancercancer survivorshiphealth disparitiesinsomniamediation use disparitiesmedicationnauseapancreatic cancersupportive care

Identifiers

PMID41785943
PMCPMC13066928

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.