Observational studyBMC cardiovascular disorders2026
Left atrial function in class III obesity: a pilot study using two-dimensional speckle tracking echocardiography.
Observational study in BMC cardiovascular disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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14 authors.
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Abstract
introductionCurrently, the interaction between heart failure with preserved ejection fraction (HFpEF) and obesity is discussed. As part of a complex echocardiographic examination, the two-dimensional speckle tracking (2D-STE) method is a significant tool for assessing dysfunction of the left atrium. Our study aimed to compare left atrial function using the 2D-STE in patients with class III obesity and a control group.
methodsThis was an observational, prospective, pilot /preliminary/ study that enrolled 20 patients with class III obesity (Body mass index (BMI) > 40 kg/m²) and a group of nineteen healthy individuals with a BMI of 20–25 kg/m² as controls. The following parameters were observed: Reservoir Left Atrial Strain (R-LAS), Conduit Time (CT-LAS), and Contractile Displacement (CD-LAS).
resultsThe study patient group included sixteen women and four men (average age 42.4 years, ranging 19–63). The mean BMI was 47.69 ± 8.86 kg/m². The control group was created from fifteen women and four men (average age 27.2 ± 3.7 years, average BMI 22.48 kg/m²). The study found significant differences in R-LAS (29.9 ± 7.0 vs. 45.0 ± 11.7;p < 0.001) and CT-LAS (-16.8 ± 5.89 vs. -29.7 ± 8.71;p < 0.001) between patients with class III obesity and controls. No significant difference was seen in the remaining studied parameter /CD-LAS/ (-13.2 ± 4.77 vs. -15.1 ± 6.28;p = 0.305).
conclusionThe R-LAS and CT-LAS were significantly changed (reduced) in patients with class III obesity compared to the controls.
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