Evidence mapPaperPMID 41787759Full record

ArticleInternational journal of rheumatic diseases2026

Osteoporosis and Chronic Inflammation: A Global Bibliometric Analysis Between 1994 and 2025.

I-Hsiu Liou, Wan-Yun Huang, Sheng-Hui Tuan, Wen-Hsin Chang, Lennex Hsueh-Lin Yu, Shu-Fen Sun

Abstract readHistorical Article
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Article in International journal of rheumatic diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

I-Hsiu LiouDepartment of Physical Medicine and Rehabilitation, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.ORCID https://orcid.org/0000-0001-7754-2957
Wan-Yun HuangDepartment of Physical Medicine and Rehabilitation, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
Sheng-Hui TuanDepartment of Rehabilitation Medicine, Cishan Hospital, Ministry of Health and Welfare, Kaohsiung, Taiwan.
Wen-Hsin ChangDivision of Hematology & Oncology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Lennex Hsueh-Lin YuIndependent Researcher, Taipei, Taiwan.ORCID https://orcid.org/0000-0002-7492-5570
Shu-Fen SunDepartment of Physical Medicine and Rehabilitation, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOsteoporosis is increasingly recognized as a systemic disease influenced by chronic inflammation. The interdisciplinary nature of research in this field necessitates a comprehensive mapping of its evolution, contributors, and thematic trends.

aimTo perform a bibliometric analysis of global research on osteoporosis and chronic inflammation from 1994 to 2025, identifying publication patterns, key contributors, and emerging research themes.

methodsPublications were retrieved from Scopus using the terms "chronic inflamm*" and "osteoporo*." Eligible records included original research articles, reviews, conference papers, and editorials. Data were analyzed using bibliometrix (biblioshiny), VOSviewer, and Harzing's Publish or Perish to assess publication trends, geographical contributions, authorship patterns, journal metrics, keyword co-occurrence, and thematic evolution.

resultsA total of 1464 documents from 855 journals were analyzed, authored by 6777 individuals. The average annual growth rate was 13.45%, with a collaboration index of 5.13 and an international collaboration rate of 16.8%. The United States of America led in total citations, while Malaysia, Lebanon, and Austria had the highest average article citations. Most prolific authors and top-cited works were concentrated in academic or governmental institutions, with limited industry-affiliated corresponding author representation identified in the dataset. Osteoporosis-focused journals achieved higher citation impact compared to multidisciplinary journals. Keyword analysis revealed three major thematic clusters: mechanistic/immunological underpinnings, clinical diagnostics/risk factors, and pharmacological interventions/comorbidities, with thematic evolution showing a shift toward interdisciplinary integration since 2014.

conclusionResearch on chronic inflammation and osteoporosis has expanded rapidly, integrating mechanistic, clinical, and translational perspectives. Our findings indicate that chronic inflammation has increasingly shifted from a peripheral topic toward a central organizing theme within osteoporosis research, reflecting growing integration between immunological and bone-centric research traditions.

Indexed as

BibliometricsBiomedical ResearchInflammationOsteoporosisPeriodicals as TopicChronic DiseaseHistory, 20th CenturyHistory, 21st CenturyHumansTime Factorsbibliometric analysischronic inflammationosteoporosisresearch trends

Identifiers

PMID41787759
PMCPMC12963716

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.