Evidence map›Paper›PMID 41787963›Full record

ArticleBioinformatics (Oxford, England)2026

PEtab-GUI: a graphical user interface to create, edit, and inspect PEtab parameter estimation problems.

Paul J Jost, Frank T Bergmann, Daniel Weindl, Jan Hasenauer

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Paul J JostBonn Center for Mathematical Life Sciences, University of Bonn, Bonn 53115, Germany.ORCID 0000-0001-7613-6244
Frank T BergmannBioQUANT, Heidelberg University, Heidelberg 69120, Germany.ORCID 0000-0001-5553-4702
Daniel WeindlBonn Center for Mathematical Life Sciences, University of Bonn, Bonn 53115, Germany.ORCID 0000-0001-9963-6057
Jan HasenauerBonn Center for Mathematical Life Sciences, University of Bonn, Bonn 53115, Germany.ORCID 0000-0002-4935-3312

Funding

Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) 432325352-SFB 1454Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) 450149205-TRR 333Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) 528702961Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) EXC 2047-390685813Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) EXC 2151-390873048German Network for Bioinformatics Infrastructure W-de.NBI-016LIBISUniversity of Bonn
6 · The paper itself

Abstract

motivationParameter estimation is a cornerstone of data-driven modeling in systems biology. Yet, constructing such problems in a reproducible and accessible manner remains challenging. The PEtab format has established itself as a powerful community standard to encode parameter estimation problems, promoting interoperability and reusability. However, its reliance on multiple interlinked files-often edited manually-can introduce inconsistencies, and new users often struggle to navigate them. Here, we present PEtab-GUI, an open-source Python application designed to streamline the creation, editing, and validation of PEtab problems through an intuitive graphical user interface. PEtab-GUI integrates all PEtab components, including SBML models and tabular files, into a single environment with live error checking and customizable defaults. Interactive visualization and simulation capabilities enable users to inspect the relationship between the model and the data. PEtab-GUI lowers the barrier to entry for specifying standardized parameter estimation problems, making dynamic modeling more accessible, especially in educational and interdisciplinary settings. AVAILABILITY AND IMPLEMENTATION: PEtab-GUI is implemented in Python, open-source under a 3-Clause BSD license. The code, designed to be modular and extensible, is hosted on https://github.com/PEtab-dev/PEtab-GUI, available as a Zenodo repository at https://doi.org/10.5281/zenodo.15355752, and can be installed from PyPI.

Indexed as

Computer GraphicsSoftwareSystems BiologyUser-Computer Interface

Identifiers

PMID41787963
PMCPMC13012594

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.