SynthesisAlpha psychiatry2026
Relationship Between Negative Cognition and Poor Quality of Life and Anxiety in Adolescents: A Meta-Analysis.
Synthesis in Alpha psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
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Authors and funding
2 authors.
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Abstract
Background: Anxiety disorders are among the most prevalent psychiatric conditions during adolescence and are closely associated with maladaptive cognitive processes and impaired quality of life (QoL). However, the magnitude of these associations and the factors moderating them remain inconsistent across studies. This meta-analysis aimed to synthesize the available empirical evidence on the relationships between negative cognitions, QoL, and anxiety in adolescents, and to examine potential moderating variables. Methods: In accordance with the PRISMA 2020 guidelines, a systematic literature search was conducted across PubMed, Embase, PsycINFO, Web of Science, Scopus, and grey literature sources. Eligible studies included adolescents aged 10-19 years and reported correlation coefficients between negative cognitions or QoL and anxiety. A total of 42 studies (N = 27,845) were included and pooled using random-effects models, with Fisher's z-transformed correlation coefficients as the primary effect size. Moderator analyses examined the influence of measurement instruments, sample characteristics (clinical vs. non-clinical), age, gender distribution, and study quality. Results: Across 34 studies (n = 21,006), negative cognitions showed a moderate positive association with anxiety (r = 0.41, 95% CI: 0.37-0.45, Conclusion: Negative cognitions and reduced quality of life are robustly associated with anxiety in adolescents, particularly in clinical samples and in studies with a predominance of female participants. These findings provide strong support for cognitive-behavioral models of adolescent anxiety and underscore the importance of integrating cognitive restructuring with quality-of-life-enhancing strategies in prevention and intervention programs. Future longitudinal and cross-cultural research is needed to clarify causal mechanisms and to optimize mental health care for adolescents.
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