ReviewFrontiers in microbiology2026
The structure and function of membrane protein in coronavirus infection and its applications in the development of vaccines and therapeutic drugs.
Review in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Hitting Coronaviruses Where It Hurts: Antiviral Strategies Targeting Viral Proteins.ChemMedChem · 2026Review
- Identification of Potential SARS-CoV-2 Main Protease (MPro) Inhibitors Through Pharmacophore Modeling, Molecular Docking, and Molecular Dynamics Simulation Approaches.International journal of molecular sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coronaviruses have long posed significant harm to human and animal health, causing a variety of diseases. The membrane (M) protein of coronaviruses is one of the four major structural proteins and a key component of the viral structure, playing an important role in viral assembly, budding, and immunomodulation. In this paper, we systematically reviewe the structural and functional characteristics of the M protein, including its three transmembrane domains, N-terminal glycosylation and C-terminal oligomerization domain. In terms of function, we focus on the mechanistic roles of the M protein in viral envelope formation and the nucleocapsid packaging, as well as the newly discovered immune evasion strategy of regulating host innate immune signaling pathways. In addition, we also summarize the applications of M protein in preventing and controlling coronavirus infection and mitigating its adverse effects.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.