Evidence map›Paper›PMID 41788383›Full record

ReviewLe infezioni in medicina2026

Pulmonary edema in Dengue: a systematic review and meta-analysis.

Rachana Mehta, Abhinav Bhattarai, Ranjit Sah, Muhammad Aaqib Shamim, Shriyansh Srivastava, Aroop Mohanty, Camila Luna, D Katterine Bonilla-Aldana, Jack Feehan, Vasso Apostolopoulos and 1 more

Abstract readReview
In one paragraph

Review in Le infezioni in medicina, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rachana MehtaSR Sanjeevani Hospital, Siraha, Nepal.
Abhinav BhattaraiBeckman Research Institute, City of Hope, Duarte, CA, USA.
Ranjit SahDepartment of Medicine, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed-to-be-University), Pimpri, Pune Maharashtra, India.
Muhammad Aaqib ShamimAll India Institute of Medical Sciences Jodhpur, India.
Shriyansh SrivastavaSchool of Medical and Allied Sciences, Galgotias University, Greater Noida, India.
Aroop MohantyAIIMS Gorakhpur, Uttar Pradesh, India.
Camila LunaFaculty of Health Sciences, Universidad Científica del Sur, Lima, Peru.
D Katterine Bonilla-AldanaCollege of Medicine, Korea University, Seoul, Republic of Korea.
Jack FeehanSchool of Health and Biomedical Sciences at RMIT University, Melbourne, Australia.
Vasso ApostolopoulosSchool of Health and Biomedical Sciences at RMIT University, Melbourne, Australia.
Alfonso J Rodriguez-MoralesFaculty of Health Sciences, Universidad Científica del Sur, Lima, Peru.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pulmonary edema is a potentially life-threatening complication of dengue. The recorded incidence of pulmonary edema has varied widely between studies. Therefore, we aimed to systematically review the literature on this topic and, through meta-analysis, estimate the pooled incidence of pulmonary edema in dengue using published data. Methods: A systematic search of the PubMed, Scopus, and Web of Science databases was conducted from January 2000 to February 2025, in accordance with the PRISMA 2020 guidelines. Studies reporting the incidence of pulmonary edema in patients with dengue were included. Pooled incidence estimates for pulmonary edema in dengue were calculated via meta-analysis in R version 4.3.2 using a random-effects model. Results: Our search revealed 432 results, of which five studies met our inclusion criteria. The incidence of pulmonary edema among dengue patients varied across studies, ranging from low to moderate. We observed minimal risk of bias across studies. Our meta-analysis found a pooled incidence of pulmonary edema in dengue of 9.14% [95% CI = 6.98%-11.89%]. Conclusion: Our investigation suggests that a non-negligible proportion of dengue patients may develop pulmonary edema. Acknowledging the risk of pulmonary edema and monitoring it are essential to ensuring effective prevention of pulmonary morbidity in dengue. Additionally, we suggest that clinicians assess for underlying dengue infection when managing pulmonary edema, particularly in regions at high risk.

Indexed as

denguedengue feverincidencepulmonary complicationpulmonary edema

Identifiers

PMID41788383
PMCPMC12959632

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.