ArticleFrontiers in cardiovascular medicine2026
Association between creatinine-to-body weight ratio and arterial stiffness: a cross-sectional and longitudinal study in the Chinese population.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Few studies have explored the relationship between the creatinine-to-body weight ratio (Cre/BW) and arterial stiffness. Consequently, this research aimed to investigate the association in the Chinese population. This investigation used data from the Asymptomatic Polyvascular Abnormalities Community (APAC) study, where brachial-ankle pulse wave velocity (baPWV) was measured. After a 2-year follow-up period, 1,651 individuals participated in the longitudinal analysis, among whom 464 people had baPWV ≥1,400 cm/s. Multivariable-adjusted logistic regression was employed to calculate the odds ratios (ORs) and 95% confidence intervals (CIs) for the risk of arterial stiffness. The findings from both the cross-sectional and longitudinal analyses were largely in agreement, with the fully adjusted ORs in the highest tertile of the Cre/BW ratio being 1.36 (95% CI, 1.21-1.64) and 2.09 (95% CI, 1.52-2.87), respectively. Restricted cubic splines (RCS) analyses revealed a J-shaped associated in both cross-sectional and longitudinal studies. Subgroup analysis showed that the associations were stronger in participants younger than 60 years (1.40; 95% CI, 1.15-1.71,
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