Combining trauma therapy with computer-based neurocognitive training in soldiers with post-traumatic stress disorder: a quasi-experimental study on symptom reduction and long-term memory functions.

Introduction: Cognitive training has the potential to reduce symptoms of Post-Traumatic Stress Disorder (PTSD), but its effects on memory dysfunctions related to the disorder remain unclear. Goal of this study was to examine if a computer-based neurocognitive training (c-bnt) improves verbal and visuospatial long-term memory and reduces PTSD and depressive symptoms in active soldiers with PTSD. Methods: In a quasi-randomized controlled design, soldiers suffering from PTSD were assigned to an intervention group (IG) or treatment as usual group (tauG). Long-term memory performance was assessed using the Verbal Learning and Memory Test (VLMT) and Visual Path Learning Test (VWLT) at baseline and after a three-week intervention period. Severity of PTSD symptoms and depression was assessed with the Results: Compared to the tauG, the IG showed significant reductions in the PTSD symptoms avoidance ( Discussion and Conclusion: C-bnt was associated with modest, domain-specific reductions in PTSD-related avoidance and depressive symptoms at post-treatment, while no improvements in verbal or visuospatial long-term memory performance were observed. Symptom relief may thus be based on intermingled changes of diverse cognitive resources and emotional processes. We suggest that c-bnt may serve as a low-threshold adjunct to trauma-focused therapy, that may help to improve health condition and capabilities of everyday life in soldiers with PTSD.