Evidence map›Paper›PMID 41789063›Full record

ReviewFrontiers in immunology2026

The role of Piezo1 in immune cells and pregnancy.

Yiming Fei, Yilin Liu, Lijuan Zhang

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yiming FeiDepartment of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Yilin LiuDepartment of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Lijuan ZhangDepartment of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In innate immunity, Piezo1 influences macrophage polarization, neutrophil migration, inflammation and repair. In adaptive immunity, it modulates T cell mechanosensation, immune synapse formation and B cell antigen presentation. Expressed in endometrium, placental vasculature, placental trophoblast and myometrium, Piezo1 regulates Ca²

Indexed as

Ion ChannelsMacrophagesAdaptive ImmunityAnimalsFemaleHumansImmunity, InnateMechanotransduction, CellularPlacentaPregnancyIon ChannelsPIEZO1 protein, humanadaptive immune responsesimmune cellsinnate immune systemPiezo1pregnancy

Identifiers

PMID41789063
PMCPMC12956649

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.