Evidence map›Paper›PMID 41789100›Full record

ArticleFrontiers in immunology2026

Tick lipocalin triggers mammalian IGFBP-3-mediated apoptosis in macrophages and keratinocytes.

Krittika Nandy, P P Mahesh, Lichao Liu, Daniel E Sonenshine, Hameeda Sultana, Girish Neelakanta

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Krittika NandyDepartment of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN, United States.
P P MaheshDepartment of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN, United States.
Lichao LiuDepartment of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN, United States.
Daniel E SonenshineDepartment of Biological Sciences, Old Dominion University, Norfolk, VA, United States.
Hameeda SultanaDepartment of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN, United States.
Girish NeelakantaDepartment of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN, United States.

Funding

Anaplasma Phagocytophilum Modulate Tick Gene Expression for its Survival and Transmission from the Vector HostR01AI130116 · NIAID · UNIVERSITY OF TENNESSEE KNOXVILLE · PI Girish Neelakanta · 2017 to 2026
$3.0M
NIAID NIH HHS R01 AI130116
6 · The paper itself

Abstract

Ticks secrete several molecules, including lipocalins, in their saliva during blood feeding on a vertebrate host. In this study, we provide novel evidence on the role of

Indexed as

ApoptosisArthropod ProteinsInsulin-Like Growth Factor Binding Protein 3KeratinocytesLipocalinsMacrophagesTicksAnimalsCell LineCytokinesHumansMiceArthropod ProteinsCytokinesInsulin-Like Growth Factor Binding Protein 3Lipocalinsanti-apoptoticapoptosisBcl-2caspasescytokinesIGFBP-3lipocalinticks

Identifiers

PMID41789100
PMCPMC12956797

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.