Evidence map›Paper›PMID 41789156›Full record

ArticleFrontiers in physiology2025

Asmeton minimizes dry cough and diaphragmatic contraction during pulsed-field ablation of atrial fibrillation: a clinical prospective randomized study.

Huixing Liu, Yan Zhang, Huafen Liu, Wei Liu, Zhuo Wang, Can Leng, Gangjie Xie, Jiahao Zhao, Jinlin Huang, Lei Huang and 4 more

Abstract read
In one paragraph

Article in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Huixing Liu *Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Yan Zhang *Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Huafen Liu *Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Wei LiuDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Zhuo WangDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Can LengDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Gangjie XieDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Jiahao ZhaoDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Jinlin HuangDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Lei HuangDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Yuzhi LuDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Hongwei ZhangDepartment of Cardiology, Enshi Huiyi Hospital of Rheumatic Diseases, Enshi, China.
Songyun WangDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Hong JiangDepartment of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Pulsed-field ablation (PFA) is a novel ablation modality with promising outcomes for atrial fibrillation therapy. However, PFA might lead to dry cough and diaphragmatic contraction, especially under conscious sedation. We aim to explore a novel approach to reduce dry cough and diaphragmatic contraction during PFA procedures performed under conscious sedation. Methods: A total of 16 patients who underwent PFA pulmonary vein isolation under conscious sedation were divided into the asmeton (with preprocedure asmeton) and control groups. A scoring system was developed to assess dry cough and diaphragmatic contraction. Results: A total of 608 ablations and 893 ablations were performed in the control and asmeton groups, respectively. The dry cough score ( Conclusion: Asmeton might eliminate moderate-to-severe dry cough and reduce the severity of diaphragmatic contraction during pulmonary vein isolation under conscious sedation ablation.

Indexed as

asmetonatrial fibrillationdiaphragmatic contractiondry coughpulsed-field ablation

Identifiers

PMID41789156
PMCPMC12956715

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.