Evidence map›Paper›PMID 41789336›Full record

ReviewReviews in cardiovascular medicine2026

Navigation of the Clinical Implications, Interventional Challenges, and Complexities of the Circumflex Coronary Artery: A Comprehensive Review.

Abdelrahman Elhakim, Ahmad Hassaan, Ibrahim Yassen, Mohamed Mosaad, Mohamed Elhakim, Osama Bisht, Mahmoud Baraka, Mohammed Saad

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abdelrahman ElhakimCardiology Department, Staedtisches Klinikum Braunschweig, 38126 Braunschweig, Germany.ORCID https://orcid.org/0000-0002-3315-4167
Ahmad HassaanCardiology Department, Al-Azhar University, Nasr City, 11884 Cairo, Egypt.
Ibrahim YassenCardiology Department, Al-Azhar University, Nasr City, 11884 Cairo, Egypt.
Mohamed MosaadCardiology Department, Al-Azhar University, Nasr City, 11884 Cairo, Egypt.
Mohamed ElhakimIntensive Care Medicine Department, The Royal Prince Alfred Hospital, Sydney, NSW 2050, Australia.ORCID https://orcid.org/0000-0002-4533-160X
Osama BishtCardiology Department, Coswig Heart Center, 06869 Coswig, Germany.
Mahmoud BarakaCardiology Department, Ain Shams University, Abbaseya, 11517 Cairo, Egypt.ORCID https://orcid.org/0000-0002-6894-5268
Mohammed SaadCardiology Department, Schleswig-Holstein University Hospital-Kiel, 24105 Kiel, Germany.ORCID https://orcid.org/0000-0002-8680-3706

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The circumflex (Cx) coronary artery is more vulnerable to injury than other coronary arteries during procedures such as radiofrequency ablation, left atrial appendage closure, mitral valve repair, and coronary sinus-based mitral valve intervention. Furthermore, a lower success rate was also observed in the Cx artery during chronic occlusion recanalization. Additionally, injury to the great cardiac vein during Cx artery interventions can occur due to the highly variable and often unpredictable relationship between the great cardiac vein and the Cx artery, which occurs in approximately 30% of cases. Imaging information on the Cx artery and the associated relationship with surrounding cardiac structures is crucial for understanding spatial orientation. This knowledge aids preventive measures, accurate prediction, prompt recognition, and understanding of injury mechanisms, thereby facilitating appropriate therapeutic interventions. We present a comprehensive literature review of the clinical implications, complexities, and challenges associated with the Cx artery, which could help in management strategies and improve outcomes.

Indexed as

calcific lesionchronic total occlusioncircumflex arterycomputed tomographygreat cardiac veinintravascular ultrasoundleft atrial appendagemitral valvepercutaneous coronary interventionpericardial effusiontransthoracic echocardiography

Identifiers

PMID41789336
PMCPMC12959989

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.