Evidence map›Paper›PMID 41789582›Full record

ArticleMolecular medicine reports2026

Characteristics of chromosomal instability‑related lncRNAs associated with progression and prognosis in breast cancer.

Qi Chen, Hui Chen, Hui Yang, Yin Tao, Xiaolan Zhu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular medicine reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qi ChenMolecular Genetic Diagnostics Laboratory, Genetic and Prenatal Diagnosis Center, Fourth Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212003, P.R. China.
Hui ChenMolecular Genetic Diagnostics Laboratory, Genetic and Prenatal Diagnosis Center, Fourth Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212003, P.R. China.
Hui YangDepartment of Breast Surgery, Fourth Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212003, P.R. China.
Yin TaoMolecular Genetic Diagnostics Laboratory, Genetic and Prenatal Diagnosis Center, Fourth Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212003, P.R. China.
Xiaolan ZhuReproductive Genetics Laboratory, Reproductive Medicine Center, Fourth Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212003, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chromosomal instability (CIN), which leads to structural and numerical variations in chromosomes, plays an important role in the oncogenesis and progression of cancers. However, the functional role of CIN‑associated long non‑coding RNAs (lncRNAs) remains to be fully elucidated. Copy number variations and CIN were evaluated on the basis of aneuploidy and 70‑gene CIN‑signature scores. A CIN‑based prognostic model was constructed using univariate and multivariate Cox regression analyses. The performance of the CIN‑associated lncRNA signature was assessed using receiver operating characteristic curves and overall‑survival analyses.

Indexed as

Breast NeoplasmsChromosomal InstabilityRNA, Long NoncodingBiomarkers, TumorCell Line, TumorCell MovementCell ProliferationDisease ProgressionDNA Copy Number VariationsFemaleGene Expression Regulation, NeoplasticHumansMiddle AgedPrognosisProtein Serine-Threonine KinasesBiomarkers, TumorProtein Serine-Threonine KinasesRNA, Long Noncodingbiomarkerbreast cancerchromosomal instabilitylncRNAprognosis

Identifiers

PMID41789582
PMCPMC12994133

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.