Evidence map›Paper›PMID 41789592›Full record

ReviewMolecular medicine reports2026

Advances regarding physiological functions and mechanisms of theaflavin‑3,3'‑digallate (Review).

Teng Ma, Siwei Zhang, Miaomiao Xiao, Zhijian Ma, Junhong Guan

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Molecular medicine reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Teng Ma *Gansu Province Key Laboratory of Environmental Oncology, Cuiying Biomedical Research Center, The Second Hospital and Clinical Medical School of Lanzhou University, Lanzhou, Gansu 730030, P.R. China.
Siwei Zhang *Department of Digestive Disease, Weinan Central Hospital, Weinan, Shaanxi 714000, P.R. China.
Miaomiao XiaoGansu Province Key Laboratory of Environmental Oncology, Cuiying Biomedical Research Center, The Second Hospital and Clinical Medical School of Lanzhou University, Lanzhou, Gansu 730030, P.R. China.
Zhijian MaDepartment of Experimental Research, Sun Yat‑sen University Cancer Center, Guangzhou, Guangdong 510060, P.R. China.
Junhong GuanGansu Province Key Laboratory of Environmental Oncology, Cuiying Biomedical Research Center, The Second Hospital and Clinical Medical School of Lanzhou University, Lanzhou, Gansu 730030, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Theaflavin‑3,3'‑digallate (TF3) is a major galloylated theaflavin generated during black tea fermentation and has been reported to exhibit a range of biological activities, including antioxidant, anti‑inflammatory, antimicrobial, antiviral and anticancer properties. However, due to its chemical instability, low bioavailability and complex biotransformation in the gastrointestinal tract, the

Indexed as

BiflavonoidsCatechinAnimalsAnti-Inflammatory AgentsAntioxidantsGallic AcidHumansSignal TransductionTeaAnti-Inflammatory AgentsAntioxidantsBiflavonoidsCatechinGallic AcidTeatheaflavin-3,3'-digallatetheaflavin digallate3'‑digallatebiological activitychronic diseasesmechanismnatural producttheaflavin‑3

Identifiers

PMID41789592
PMCPMC12994445

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.