Evidence map›Paper›PMID 41789840›Full record

ArticleJournal of the American Chemical Society2026

An Automation Platform for the Chemoenzymatic Synthesis of Complex Sulfated and Branched Glycans.

Saptashwa Chakraborty, Kyle Minder, Anthony Robert Prudden, Geert-Jan Boons

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Saptashwa ChakrabortyComplex Carbohydrate Research Center, University of Georgia, Athens, Georgia 30602, United States.
Kyle MinderComplex Carbohydrate Research Center, University of Georgia, Athens, Georgia 30602, United States.
Anthony Robert PruddenComplex Carbohydrate Research Center, University of Georgia, Athens, Georgia 30602, United States.
Geert-Jan BoonsComplex Carbohydrate Research Center, University of Georgia, Athens, Georgia 30602, United States.ORCID 0000-0003-3111-5954

Funding

Automated chemo-enzymatic synthesis of N-glycans for host-pathogen interactionsR01AI165692 · NIAID · UNIVERSITY OF GEORGIA · PI BOONS, GEERT-JAN · 2022 to 2025
$2.2M
NIAID NIH HHS R01 AI165692
6 · The paper itself

Abstract

Diverse collections of well-defined glycans are needed to investigate the molecular mechanisms by which these biomolecules mediate biological and disease processes. Several automation approaches have been introduced to accelerate the enzymatic synthesis of complex glycans. These methodologies have, however, provided only relatively simple oligosaccharides due to limitations of glycosyl transferase selectivity. Here, we describe an automation platform that makes it possible, for the first time, to prepare in an automated fashion sulfated polylactosamines and asymmetric multiantennary complex

Indexed as

AutomationGlycosyltransferasesPolysaccharidesSulfatesGlycosylationGlycosyltransferasesPolysaccharidesSulfates

Identifiers

PMID41789840
PMCPMC13003436

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.