ReviewWorld journal of microbiology & biotechnology2026
Volatile fatty acids as sustainable precursors for bioproduction: advances in pathway engineering, and bioprocess optimization.
Review in World journal of microbiology & biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Substantial efforts have been dedicated to exploring alternative substrates for producing bioenergy and bioproducts, including exploring Volatile Fatty Acids (VFAs) as a promising carbon source. VFAs are short-chain organic acids with carbon chains ranging from C2 to C6. Advancements in biotechnology have enabled the metabolic engineering of microbial producers to convert VFAs into high-value biochemicals. Optimizing bioprocess parameters is as critical as genetic engineering for ensuring efficient substrate utilization and synthesis of desired product. This review provides a comprehensive summary of strategies for the utilization of VFAs as substrates for the bioproduction of a wide range of chemicals. Main topics cover mechanisms for VFA uptake and metabolism; challenges faced in VFA utilization, including toxicity, mixture complexity, and process integration; bioprocess strategies such as co-culture, feast-famine regimes, feeding techniques, and process optimization to enhance VFA valorization; and integrative electrochemical conversion with metabolic engineering approaches to improve efficiency in VFA upcycling. Overall, the review underscores the importance of advancing bioprocess and genetic strategies to unlock the full potential of VFAs for sustainable bioproduction.
Indexed as
Identifiers
41790335What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.