Evidence map›Paper›PMID 41790760›Full record

ArticlePloS one2026

Feasibility of MEG in assessing task-related oscillatory markers and evaluating cognitive changes in recently symptomatic carotid endarterectomy patients: A pilot study.

Tiia Kukkonen, Sanna Liuha, Juha Leukkunen, Hanna-Maija Lapinkero, Ilmari Rouvinen, Simo Monto, Tiina Parviainen

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tiia KukkonenDepartment of Surgery, Hospital Nova of Central Finland, Wellbeing Services County of Central Finland, Jyväskylä, Finland.ORCID https://orcid.org/0000-0003-3349-7685
Sanna LiuhaDepartment of Neurology, Hospital Nova of Central Finland, Wellbeing Services County of Central Finland, Jyväskylä, Finland.
Juha LeukkunenCenter for Interdisciplinary Brain Research, Department of Psychology, Faculty of Education and Psychology, University of Jyväskylä, Jyväskylä, Finland.
Hanna-Maija LapinkeroCenter for Interdisciplinary Brain Research, Department of Psychology, Faculty of Education and Psychology, University of Jyväskylä, Jyväskylä, Finland.
Ilmari RouvinenCenter for Interdisciplinary Brain Research, Department of Psychology, Faculty of Education and Psychology, University of Jyväskylä, Jyväskylä, Finland.
Simo MontoCenter for Interdisciplinary Brain Research, Department of Psychology, Faculty of Education and Psychology, University of Jyväskylä, Jyväskylä, Finland.
Tiina ParviainenCenter for Interdisciplinary Brain Research, Department of Psychology, Faculty of Education and Psychology, University of Jyväskylä, Jyväskylä, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Revascularization ensures oxygen supply to the brain in patients with significant carotid atherosclerosis. The current indication for carotid endarterectomy (CEA) is stroke risk reduction, but it may also impact cognitive functions and their neural basis. Findings on cognitive outcomes after CEA are inconsistent, and the changes in task-related brain electrophysiology are unknown. In this pilot study, we studied the feasibility of using magnetoencephalography (MEG) to follow the associated brain changes during the first postoperative year in five recently symptomatic CEA patients. Head magnetic resonance imaging (MRI), neuropsychological examinations (NPE), and MEG were performed prior to surgery and repeated twice postoperatively. The stimulus-induced modulation of cortical alpha oscillation changed from pre- to 12 months postoperative recording in simple attention tasks. Neuropsychological examination pointed to improvement in postoperative motor dexterity and working memory. Our tentative results suggest that MEG may provide a useful means to evaluate CEA-related changes in the brain. Additional analyses in larger samples with age-matched controls are required to confirm the link between the changes in brain function and possible improvement in cognitive function in these patients. Increased understanding of the consequences of CEA on brain function and cognition is important both to clinicians and patients.

Indexed as

CognitionEndarterectomy, CarotidMagnetoencephalographyAgedFeasibility StudiesFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedNeuropsychological TestsPilot Projects

Identifiers

PMID41790760
PMCPMC12965589

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.