Evidence map›Paper›PMID 41792205›Full record

ArticleScientific reports2026

A nutritional risk index-based nomogram for predicting prognosis and identifying induction chemotherapy beneficiaries in nasopharyngeal carcinoma.

Sunqin Cai, Jue Wang, Ying Li, Zongwei Huang, Sundong Cai, Sufang Qiu, Jingjing Su

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sunqin Cai *Department of Radiation Oncology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Jue Wang *Department of Radiation Oncology, Fujian Cancer Hospital, NHC Key Laboratory of Cancer Metabolism, Clinical Oncology School of Fujian Medical University, Fuzhou, China.
Ying Li *Department of Radiation Oncology, Fujian Cancer Hospital, NHC Key Laboratory of Cancer Metabolism, Clinical Oncology School of Fujian Medical University, Fuzhou, China.
Zongwei HuangDepartment of Radiation Oncology, Fujian Cancer Hospital, NHC Key Laboratory of Cancer Metabolism, Clinical Oncology School of Fujian Medical University, Fuzhou, China.
Sundong CaiDepartment of Emergency, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Sufang QiuDepartment of Radiation Oncology, Fujian Cancer Hospital, NHC Key Laboratory of Cancer Metabolism, Clinical Oncology School of Fujian Medical University, Fuzhou, China. sufangqiu@fjmu.edu.cn.
Jingjing SuDepartment of Radiation Oncology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China. sjjyiwei@163.com.

Funding

Major Scientific Research Program for Young and Middle-aged Health Professionals of Fujian Province 2021ZQNZD010National Natural Science Foundation of China 82473376Startup Fund for scientific research, Fujian Medical University 2020QH1107
6 · The paper itself

Abstract

This study was designed to assess the prognostic significance of nutritional risk index (NRI) in nasopharyngeal carcinoma (NPC) patients. In this dual-center study, 1,174 patients were enrolled. Kaplan-Meier analysis assessed the association between NRI and prognosis. Independent prognostic factors for nomogram construction were identified using multivariate Cox regression analysis. The predictive nomogram underwent assessment through decision curve analysis (DCA) and calibration curves. The median NRI value was 112.11. Patients with high NRI (≥ 112.11) demonstrated significantly better survival outcomes than those with low NRI (< 112.11) in both cohorts. Multivariate analysis identified that NRI (≥ 112.11 vs. < 112.11) was an independent prognostic factor for distant metastasis-free survival in the training cohort, and for overall survival (OS) and locoregional relapse-free survival in the validation cohort. The constructed nomogram showed strong discriminatory ability (C-index: 0.715 for training; 0.678 for validation) and good calibration. DCA indicated superior clinical net benefit compared to default strategies. Risk stratification revealed that low-risk patients achieved significantly higher 3-year OS (97.8% vs. 81.1%, P < 0.001) and progression-free survival (PFS, 93.0% vs. 69.3%, P < 0.001) than high-risk patients. Within the high-risk group, the induction chemotherapy (IC) plus radiotherapy (RT)/concurrent chemoradiotherapy (CCRT) regimen significantly improved OS and PFS compared to RT/CCRT alone. Among low-risk patients, the two regimens yielded comparable outcomes. The NRI serves as a reliable prognostic indicator for NPC patients. The proposed nomogram enables personalized risk stratification and offers reference for individual treatment regimen selection.

Indexed as

Induction ChemotherapyNasopharyngeal CarcinomaNasopharyngeal NeoplasmsNomogramsNutrition AssessmentAdultAgedFemaleHumansKaplan-Meier EstimateMaleMiddle AgedPrognosisInduction chemotherapyNasopharyngeal carcinomaNomogram modelNutritional risk index

Identifiers

PMID41792205
PMCPMC12988130

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.