ReviewApoptosis : an international journal on programmed cell death2026
Metrnl in health and disease: tissue-specific actions and signaling networks.
Review in Apoptosis : an international journal on programmed cell death, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Metrnl in diabetes and its complications: divergent evidence and translational prospects.Journal of translational medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
Emerging as a novel secreted protein, Meteorin-like (Metrnl) exhibits substantial sequence homology with Meteorin (Metrn). Although Metrnl was initially identified in the context of adipose tissue and metabolic regulation, accumulating evidence has demonstrated its widespread expression across multiple tissues, including the nervous system, barrier tissues, and skeletal muscle. Functionally, Metrnl exerts pleiotropic biological effects and has been implicated as an adipokine, an immunomodulatory factor, and a cytoprotective mediator. This review provides an overview of current knowledge regarding the tissue-specific actions of Metrnl and summarizes the major signaling pathways associated with its activity. The integral role of Metrnl across different systems in both health and disease states is further examined, with a focus on elucidating its pathological involvement in various human disorders.
Indexed as
Identifiers
41793514What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.