ArticleBJOG : an international journal of obstetrics and gynaecology2026
Maternal Obesity, Gestational Diabetes Mellitus and Offspring's Body Mass Index Trajectories From Birth to Age 6 Years: Glucose in Relation to Women and Babies' Health (GrownB) Study.
Article in BJOG : an international journal of obstetrics and gynaecology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo examine whether offspring born to mothers with overweight/obesity, gestational diabetes mellitus (GDM) or both exhibit different body mass index (BMI) trajectories from birth to 6 years old.
designRetrospective cohort study.
settingThe Glucose in Relation to Women and Babies' Health (GrownB) Study at the University of California, Los Angeles (UCLA) Medical Center. POPULATION OR SAMPLE: Twenty thousand four hundred fifty six mother-offspring pairs.
methodsMothers were classified as normal-weight & non-GDM (NWN), normal-weight & GDM (NWG), overweight/obesity & non-GDM (OWN) or overweight/obesity & GDM (OWG). Offspring BMI trajectories were estimated using linear mixed-effects models in two age periods (0-24 months and 2-6 years), adjusting for confounding.
main outcome measuresWe extracted offspring's birth weight, recumbent length (age < 2 years) or standing height (age ≥ 2 years), and weight data from routine clinical encounters and physical examinations from the UCLA electronic health records.
resultsOffspring of mothers with overweight/obesity had higher BMI trajectories than those of normal-weight mothers across both 0-24 months (BMI mean differences overall 0-24 months: 0.28 [0.17, 0.39] kg/m
conclusionsMaternal pre-pregnancy overweight/obesity was associated with higher offspring BMI trajectories from birth to age of 6 years, while the association was not observed for GDM.
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