ArticleJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine2026
Diagnostic Performance of Duplex Ultrasonography in Post-Radiation Common Carotid Artery Stenosis: A Cross-Sectional Validation Study.
Article in Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
objectivesWhether established diagnostic criteria of carotid duplex ultrasonography (CDU) for atherosclerotic carotid artery stenosis are applicable to radiation vasculopathy in head and neck cancer (HNC) patients remains uncertain. This study aimed to validate the diagnostic accuracy of CDU for screening radiation-induced common carotid artery (CCA) stenosis.
methodsWe enrolled 134 HNC patients with 268 carotid arteries, all of whom underwent CDU and computed tomographic angiography. Diameter stenosis and hemodynamic parameters were assessed on CDU, with ≥50% stenosis on computed tomographic angiography serving as the reference standard. Diagnostic performance was evaluated using sensitivity, specificity, PPV, NPV, and receiver operating characteristic (ROC) analysis to identify optimal cutoff values.
resultsUsing a B-mode cutoff of 50% to detect ≥50% CCA stenosis, the sensitivity, specificity, PPV, and NPV were 85.2, 88.1, 45.1, and 98.1%, respectively. The optimal B-mode threshold of 53%, which yielded a sensitivity of 75.9%, specificity of 91.4%, PPV of 51.2%, and NPV of 96.9%, with an area under the ROC curve (AUROC) of 0.894. In comparison, the optimal PSV threshold of 203 cm/s showed lower sensitivity (51.7%) but higher specificity (99.2%), with a PPV of 88.2%, NPV of 94.6%, and an AUROC of 0.698. Combining B-mode and PSV criteria resulted in an AUROC of 0.891, offering minimal incremental diagnostic benefit compared with B-mode assessment alone.
conclusionsB-mode CDU may be a feasible screening tool for radiation-induced CCA stenosis. A B-mode threshold of 53% achieved diagnostic performance comparable to combined B-mode and velocity criteria for detecting ≥50% stenosis.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.