Evidence map›Paper›PMID 41797169›Full record

ArticleTalanta2026

Evaluation of fluorescein benzoate di/tri/tetrasulfides as potential chemical tools and probes for reactive sulfur species.

Yuqing Wang, Austin Sarker-Young, Stephen Lindahl, Meg Shieh, Ming Xian

Abstract read
In one paragraph

Article in Talanta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuqing WangDepartment of Chemistry, Brown University, Providence, RI, 02912, USA.
Austin Sarker-YoungDepartment of Chemistry, Brown University, Providence, RI, 02912, USA.
Stephen LindahlDepartment of Chemistry, Brown University, Providence, RI, 02912, USA.
Meg ShiehDepartment of Chemistry, Brown University, Providence, RI, 02912, USA.
Ming XianDepartment of Chemistry, Brown University, Providence, RI, 02912, USA. Electronic address: ming_xian@brown.edu.

Funding

Explore the Chemistry and Chemical Biology of Reactive Sulfur SpeciesR35GM149170 · NIGMS · BROWN UNIVERSITY · PI Ming Xian · 2023 to 2026
$1.6M
NIGMS NIH HHS R35 GM149170
6 · The paper itself

Abstract

Reactive sulfur species (RSS) play vital roles in biological redox regulation but remain challenging to detect selectively. In this work, we prepared and tested fluorescein benzoate disulfide (SPS2), trisulfide (SPS3), and tetrasulfide (SPS4) as possible fluorescent probes for RSS. All these compounds exhibited good stability in aqueous buffers. The disulfide compound (SPS2) was found to be least reactive, and it only reacted with hydrogen disulfide (H

Indexed as

DisulfideFluorescenceHydrogen persulfidePolysulfideReactive sulfur species

Identifiers

PMID41797169
PMCPMC13220694

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.