Observational studyJournal of rehabilitation medicine2026
Recruitment of the central nervous system in different hand tasks in patients with hand dysfunction after stroke based on functional near-infrared spectroscopy: an exploratory study.
Observational study in Journal of rehabilitation medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Prefrontal activation and connectivity during verbal fluency in autism Spectrum disorder: an fNIRS study.Frontiers in human neuroscience · 2026Article
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to examine the central nervous system activation in stroke patients with hand dysfunction during various hand tasks, reflecting central nervous system recruitment.
designA single-centre cross-sectional observational study. PATIENTS: This research selected stroke patients with hand dysfunction hospitalized in the authors' hospital from October 2022 to November 2023. Participants were aged 25-75 years, with a post-stroke duration ranging from 2 to 24 weeks.
methodsA 35-channel functional near-infrared spectroscopy system was used to record cortical activity during the resting state, affected-hand grasping tasks, and hand-crank cycling tasks. The study compared the average brain activation extent and functional connectivity between grasping and handbike tasks, focusing on the primary sensorimotor cortex, dorsolateral prefrontal cortex, primary motor cortex, and primary somatosensory cortex as regions of interest.
resultsComparative analysis of brain region activation revealed significant increases in activation across all regions of interest compared with the resting state (p < 0.001). When comparing grasping with handbike tasks, significant increases in activation were observed in all regions of interest except the right primary somatosensory cortex (p < 0.05). Additionally, the right dorsolateral prefrontal cortex exhibited stronger functional connectivity with bilateral primary motor cortex, primary sensorimotor cortex, and left primary somatosensory cortex during the grasping task compared with the handbike task (p < 0.05).
conclusionThis study shows that grasping tasks recruit cognitive, sensory, and motor cortex activities in stroke patients with hand dysfunction relatively higher than handbike tasks.
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