Evidence map›Paper›PMID 41798127›Full record

ArticleNeuro-oncology practice2026

Tele-cognitive rehabilitation for adult lower-grade glioma: An interim prospective pilot feasibility study.

Christina Weyer-Jamora, Melissa S Brie, Paige M Bracci, Ellen M Smith, Tracy L Luks, Stephanie Phan, Steve E Braunstein, Nancy Ann Oberheim-Bush, Nicholas A Butowski, Jennifer L Clarke and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuro-oncology practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Christina Weyer-JamoraDepartment of Psychiatry, Zuckerberg San Francisco General Hospital, San Francisco, California, USA.ORCID https://orcid.org/0000-0002-7729-0320
Melissa S BrieDepartment of Psychiatry, Zuckerberg San Francisco General Hospital, San Francisco, California, USA.
Paige M BracciDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, California, USA.
Ellen M SmithDepartment of Neurological Surgery, University of California San Francisco, San Francisco, California, USA.
Tracy L LuksDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.
Stephanie PhanDepartment of Neurological Surgery, University of California San Francisco, San Francisco, California, USA.
Steve E BraunsteinDepartment of Radiation Oncology, University of California San Francisco, San Francisco, California, USA.
Nancy Ann Oberheim-BushDepartment of Neurology, University of California San Francisco, San Francisco, California, USA.
Nicholas A ButowskiDepartment of Neurological Surgery, University of California San Francisco, San Francisco, California, USA.
Jennifer L ClarkeDepartment of Neurology, University of California San Francisco, San Francisco, California, USA.
Karin GehringDepartment of Cognitive Neuropsychology, Tilburg University, Tilburg, Netherlands.
Adrian Aguilera
John de GrootDepartment of Neurological Surgery, University of California San Francisco, San Francisco, California, USA.ORCID https://orcid.org/0000-0003-1454-6461
Susan M ChangDepartment of Neurological Surgery, University of California San Francisco, San Francisco, California, USA.ORCID https://orcid.org/0000-0003-3521-364X
Shawn L Hervey-JumperDepartment of Neurology, University of California San Francisco, San Francisco, California, USA.
Jennie W TaylorDepartment of Neurology, University of California San Francisco, San Francisco, California, USA.ORCID https://orcid.org/0000-0003-3980-5626

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cognitive impairments are common in lower-grade gliomas (grades 1-3), but treatment options are limited. Tele-cognitive rehabilitation offers a potential solution. We conducted an interim pilot study to assess the feasibility, satisfaction, and early efficacy of tele-cognitive rehabilitation. Methods: We enrolled adults with stable LrGG (≥6 months posttreatment) who had subjective and objective cognitive impairments (>1 SD below-average in ≥2 domains). Participants received 3 months of individual Goal Management Training (GMT), app-based ReMind, or texting. Cognition and patient-reported outcomes were assessed at baseline (T1), postintervention (T2), and 9 months postbaseline (T3). We assessed enrollment, adherence, and satisfaction. Adherence was defined as ≥80% of participants completing ≥80% of the protocol; satisfaction as ≥6/7 for GMT and texting, and ≥4/5 for ReMind on a self-report Likert question. We used ANOVA, reliable change indices, and qualitative analytics. Results: Thirty-nine participants were eligible and 33 prospectively enrolled for the study; an 85% enrollment (17-GMT, 8-ReMind, 8-texting; 46.8 median age, 64.8 months from diagnosis, 55% had astrocytoma, and 76% had prior radiotherapy). Eighty-two percent of GMT (adequate), 100% of texting (adequate), and for ReMind 33% of retraining and 50% of compensation (inadequate) completed ≥80% of the protocol. GMT (mean: 6.75/7) and ReMind (mean: 4.5/5) satisfaction were adequate, and texting (mean: 4.5/7) was inadequate. Working memory improved from T1-to-T2 ( Conclusions: GMT demonstrates adequate feasibility, satisfaction, and may yield improvements in working memory, while texting and ReMind had challenges in acceptability or feasibility. Individual (tele) GMT warrants further investigation in LrGG.

Indexed as

brain tumorcognitive rehabilitationneuropsychologytelehealth

Identifiers

PMID41798127
PMCPMC12965652

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.