Evidence mapPaperPMID 41798245Full record

ArticleIndian journal of psychiatry2026

Study of cognitive functions and heart rate variability in reproductive-age group and post-menopausal women.

Akansha Haldar, Shraddha Singh, Sujita K Kar, Renu Singh, Sudipti Yadav

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Article in Indian journal of psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Akansha HaldarDepartment of Physiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Shraddha SinghDepartment of Physiology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Sujita K KarDepartment of Psychiatry, King George's Medical University, Lucknow, Uttar Pradesh, India.
Renu SinghDepartment of Obstetrics and Gynaecology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Sudipti YadavDepartment of Physiology, King George's Medical University, Lucknow, Uttar Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The menopausal transition is associated with hormonal, cognitive, and autonomic changes, yet the interplay between cognitive function and autonomic regulation-measured via heart rate variability (HRV) remains underexplored in Indian women. Aims: The study aimed to compare cognitive performance and HRV parameters between reproductive-age and post-menopausal women, and to assess the relationship between cognitive domains and HRV indices. Methods: A cross-sectional study was conducted at a tertiary care center of Northern India, enrolling 240 healthy women (120 reproductive-age, 20-40 years; 120 post-menopausal, 45-60 years). Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA), while HRV was evaluated via 5-min resting ECG. Time-domain [standard deviation of NN interval (SDNN), root mean square of successive differences (RMSSD), proportion of NN50 (pNN50), mean RR] and frequency-domain [low-frequency (LF) and high-frequency (HF), LF/HF ratio] HRV metrics were analyzed. Results: Post-menopausal women showed significantly lower MoCA scores than reproductive-age women (22.35 ± 3.17 vs. 25.54 ± 2.34, Conclusion: Post-menopausal women exhibited cognitive deficits-particularly in executive and memory domains-alongside distinct alterations in autonomic function. Contrary to expectations, HRV parameters indicated preserved or enhanced parasympathetic modulation in the older group. These findings underscore the relevance of autonomic-cognitive coupling in aging women and support HRV can be a potential biomarker of cognitive health.

Indexed as

Autonomic nervous systemcognitive functionheart rate variabilitylow frequency to high frequency ratioMontreal cognitive assessmentpost-menopausestandard deviation of NN interval

Identifiers

PMID41798245
PMCPMC12965406

What Socratic holds

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.