Evidence map›Paper›PMID 41798441›Full record

ReviewCureus2026

The Hidden Link Between Endometriosis and Obesity: A State-of-the-Art Review.

Shefali N Desai, Christina C Reed, Yamely Mendez, Qiannan Yang, Xiaoming Guan

Abstract readReview
In one paragraph

Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shefali N DesaiObstetrics and Gynecology, Baylor College of Medicine, Houston, USA.
Christina C ReedObstetrics and Gynecology, Baylor College of Medicine, Houston, USA.
Yamely MendezResearch, Baylor College of Medicine, Houston, USA.
Qiannan YangObstetrics and Gynecology, Baylor College of Medicine, Houston, USA.
Xiaoming GuanObstetrics and Gynecology, Baylor College of Medicine, Houston, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometriosis remains an under-researched disease with a wide range of symptoms. Endometriosis reduces a woman's quality of life and professional productivity, yet its exact causes, risk factors, and treatment have yet to be elucidated. Body mass index and endometriosis have been observed to be inversely related; however, this relationship may only be a correlation rather than a causation. Obesity may play a role in the inflammation and cell proliferation associated with endometriosis through the complex signaling pathways of adipokines. A literature review was done on endometriosis and obesity to gain insight and synthesize knowledge about opportunities to improve endometriosis care, its inflammatory pathogenesis, and the treatment potential of glucagon-like peptide-1. A Boolean search was performed via the Texas Medical Center Library with keywords including "endometriosis", "adipose tissue", "obesity", "adipokines", "glucagon-like peptide-1", and "inflammation". After screening titles, abstracts, and full texts, articles were excluded due to irrelevance, lack of access to full-text, and repetition. The literature revealed that at the onset of endometriosis symptoms in obese women, chronic pelvic pain and decreased appetite could cause misdiagnosis and weight loss, lowering the incidence of endometriosis in the obese population. Poor visualization, ventilatory compromise, and conversion to laparotomy during laparoscopy hinders diagnostic quality for obese patients. Interestingly, endometriosis and obesity share similar pathological markers, including leptin, adiponectin, tumor-necrosis-factor-α, and interleukin-6. Finally, glucagon-like peptide-1 was found to decrease pro-inflammatory secretions and macrophage infiltration.

Indexed as

adipokinesadipose tissuebody mass indexendometriosisglucagon-like peptide 1inflammationminimally invasive gynecological surgeryobesity

Identifiers

PMID41798441
PMCPMC12962185

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.