ReviewCureus2026
Impact of Monomer Selection and Behavior on Transdermal Drug Delivery Systems: Regulatory and Formulation Perspectives.
Review in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review article provides a comprehensive overview of the main monomers used in transdermal drug delivery systems (TDDS), such as acrylates, methacrylates, polyethylene glycol acrylates, crosslinking monomers, and specialty monomers. It examines their impact on key quality attributes (critical quality attributes), including drug release kinetics, adhesion-cohesion balance, mechanical strength, and stability under thermal and humidity stress. The article also summarizes Food and Drug Administration and European Medicines Agency requirements for monomer characterization in regulatory submissions, details analytical techniques for measuring residual monomers and analyzing the resulting polymers, and highlights recent developments in the regulatory landscape. Monomer selection is emphasized as a vital scientific and regulatory factor that influences TDDS quality, performance, and patient safety.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.