Evidence map›Paper›PMID 41799297›Full record

ArticleToxicology reports2026

Warfarin-Durian interaction: A case study bridging clinical outcomes and metabolic profiling through metabolomics.

Natthapat Hiranchatchawal, Konwalin Wannaphueak, Piyapat Rattanasuwan, Prem Lertpongpipat, Giatgong Konguthaithip, Churdsak Jaikang, Preechaya Tajai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Natthapat HiranchatchawalFaculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Konwalin WannaphueakFaculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Piyapat RattanasuwanFaculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Prem LertpongpipatFaculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Giatgong KonguthaithipDepartment of Forensic Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Churdsak JaikangDepartment of Forensic Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Preechaya TajaiDepartment of Forensic Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Warfarin-food interactions present significant challenges in achieving optimal anticoagulation; however, comprehensive research remains limited. This preliminary study explores possible mechanisms underlying the effects of durian consumption on warfarin efficacy, based on clinical observations of international normalized ratio (INR). A cross-sectional study was conducted in patients undergoing warfarin therapy who exhibited INR exceeding the therapeutic range after repeated durian consumption (one to three pieces per day for five days to one month). Plasma samples were analyzed using proton nuclear magnetic resonance (

Indexed as

1H NMR metabolomicsDrug-food interactionMetabolitesPurine metabolismTricarboxylic acid cycle

Identifiers

PMID41799297
PMCPMC12963912

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.