ArticleAIP advances2026
Computational design of a 3D magnetic particle imaging (MPI) prototype.
Article in AIP advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
3 authors.
Funding
Abstract
Magnetic particle imaging (MPI) is an emerging imaging modality that exploits the magnetization response of magnetic nanoparticle tracers. While MPI offers substantially higher resolution compared to magnetic resonance imaging, its translation to human-scale applications remains limited. These challenges stem from the requirement of high-intensity electric currents to generate strong magnetic fields, as well as reduced field uniformity with increasing coil spacing. To overcome these barriers, comprehensive simulation studies are essential for guiding MPI prototype design and performance optimization. In this work, we present a finite element method (FEM)-based design of a three-dimensional (3D) MPI prototype. The system integrates electromagnetic coils for the selection, drive, and focus fields, along with a gradiometer configuration for signal reception. Each coil's geometry and magnetic field were first simulated independently to validate its ability to generate the desired magnetic field and subsequently combined into a full-system design with time-domain input excitation signals. This framework achieved 3D field-free point (FFP) scanning within a 20 mm
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Registered trials
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