Evidence map›Paper›PMID 41799605›Full record

ArticleAnnals of gastroenterological surgery2026

Comparison of Pre- and Postoperative Gut Microbiota Diversity in Patients With Rectal Cancer Undergoing Stoma Creation and Closure.

Yusuke Suzuki, Wataru Osumi, Kohei Taniguchi, Nahoko Kato-Kogoe, Shoichi Sakaguchi, Shota Nakamura, Yoshiro Imai, Takashi Nakano, Takaaki Ueno, Sang-Woong Lee

Abstract read
In one paragraph

Article in Annals of gastroenterological surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yusuke SuzukiDepartment of General and Gastroenterological Surgery Osaka Medical and Pharmaceutical University Takatsuki Osaka Japan.
Wataru OsumiDepartment of General, Breast and Digestive Surgery Otsu City Hospital Otsu Shiga Japan.
Kohei TaniguchiDepartment of General and Gastroenterological Surgery Osaka Medical and Pharmaceutical University Takatsuki Osaka Japan.ORCID https://orcid.org/0000-0003-0648-1370
Nahoko Kato-KogoeDepartment of Dentistry and Oral Surgery, Faculty of Medicine Osaka Medical and Pharmaceutical University Takatsuki Osaka Japan.ORCID https://orcid.org/0000-0003-3585-5714
Shoichi SakaguchiDepartment of Microbiology and Infection Control, Faculty of Medicine Osaka Medical and Pharmaceutical University Takatsuki Osaka Japan.
Shota NakamuraDepartment of Infection Metagenomics, Genome Information Research Center, Research Institute for Microbial Diseases Osaka University Suita Japan.
Yoshiro ImaiDepartment of General and Gastroenterological Surgery Osaka Medical and Pharmaceutical University Takatsuki Osaka Japan.ORCID https://orcid.org/0000-0002-6299-3381
Takashi NakanoDepartment of Microbiology and Infection Control, Faculty of Medicine Osaka Medical and Pharmaceutical University Takatsuki Osaka Japan.
Takaaki UenoDepartment of Dentistry and Oral Surgery, Faculty of Medicine Osaka Medical and Pharmaceutical University Takatsuki Osaka Japan.
Sang-Woong LeeDepartment of General and Gastroenterological Surgery Osaka Medical and Pharmaceutical University Takatsuki Osaka Japan.ORCID https://orcid.org/0000-0002-2540-0655

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: To investigate the impact of temporary stoma creation and its subsequent closure on gut microbiota composition and diversity in patients undergoing rectal cancer surgery. Methods: Nineteen patients with primary rectal cancer who underwent curative surgery were enrolled and divided into two groups: stoma ( Results: In the stoma group, alpha diversity significantly decreased after surgery ( Conclusion: Temporary stoma creation in rectal cancer surgery induces persistent alterations in gut microbiota; these alterations are characterized by reduced diversity and a shift toward a dysbiotic profile with increased pathogenic and decreased beneficial taxa. These findings highlight the potential need for microbiota-targeted strategies to mitigate long-term dysbiosis in patients undergoing stoma-related procedures.

Indexed as

16S rRNA sequencinggut microbiotarectal cancerstomastoma closure

Identifiers

PMID41799605
PMCPMC12962007

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.