Evidence mapPaperPMID 41799770Full record

ArticleInternational journal of medical sciences2026

Effects of Swimming at Different Water Temperatures on Muscle and Adipose Tissue Adaptation in Diet-Induced Obese Mice.

Tzu-Jung Chou, Chia-Wen Lu, Yi-Ju Hsu, Chi-Chang Huang, Kuo-Chin Huang

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Article in International journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Tzu-Jung ChouDepartment of Family Medicine, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, Taiwan.
Chia-Wen LuDepartment of Family Medicine, National Taiwan University Hospital, Taipei, Taiwan.
Yi-Ju HsuGraduate Institute of Sports Science, National Taiwan Sport University, Taoyuan, Taiwan.
Chi-Chang HuangGraduate Institute of Sports Science, National Taiwan Sport University, Taoyuan, Taiwan.
Kuo-Chin HuangDepartment of Family Medicine, National Taiwan University Hospital, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Obesity is a major global health concern, leading to increased risk of metabolic diseases and mortality. Swimming, as a low-impact exercise, may provide metabolic benefits. However, the influence of water temperature on the metabolic and physiological responses remains underexplored. This study investigated the effects of water temperatures on muscle and adipose tissue adaptations in high-fat diet-induced obese mice. Methods: Obese mice were subjected to swimming at different water temperatures: 15°C, 25°C, or 32°C. Changes in body and tissue weight, grip strength, exhaustive swimming performance, and key metabolic parameters were assessed. Epididymal fat pads (EFP) and gastrocnemius muscles were collected for histological analyses (muscle fiber composition and adipose tissue remodeling), gene expression ( Results: Swimming at 25°C and 32°C significantly reduced body weight and EFP weight, improved metabolic profiles and grip strength, whereas cold-water swimming (15°C) enhanced endurance performance. Histological analysis revealed reduced adipocyte size in the 25°C group, accompanied by increased oxidative (Type I) fibers across all swimming groups. Elevated Conclusion: Moderate (25°C) and warm (32°C) water temperatures are optimal for reducing obesity-related metabolic dysfunctions and enhancing muscle strength, while cold water (15°C) improves endurance through oxidative muscle adaptation.

Indexed as

Adipose TissueMuscle, SkeletalObesityPhysical Conditioning, AnimalSwimmingAdaptation, PhysiologicalAnimalsBody WeightDiet, High-FatDisease Models, AnimalHumansMaleMiceMice, ObesePeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaTemperaturePeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPpargc1a protein, mouseMetabolic adaptationMuscle fiber transitionObesitySwimming exerciseWater temperature

Identifiers

PMID41799770
PMCPMC12964579

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.