ArticleFrontiers in plant science2026
Single-cell transcriptomics reveals cellular and genetic mechanisms of alpine adaptation in
Article in Frontiers in plant science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
- Deciphering Cell-Type-Specific Transcriptional Regulation in Tomato Leaves Through Ensemble Machine Learning and Single-Cell Transcriptomics.Plants (Basel, Switzerland) · 2026Article
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9 authors.
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Abstract
Introduction: Plant development is shaped by environmental conditions, and its adaptation to climate change is crucial for biodiversity conservation. The extreme climate of the Qinghai-Tibet Plateau makes it an ideal system for studying plant adaptive strategies. Methods: We constructed a draft single-cell transcriptional atlas with putative annotation of 11 leaf cell types and identified eight co-expression gene modules linked to key cell types. Results: The leaf development spatiotemporal dynamics uncovered a developmental continuum from cell proliferation to photosynthetically specialized maturation. Furthermore, we identified several developmental and physiological features potentially associated with high-altitude adaptation, including presence of transcriptionally active nuclear-encoded genes involved in chloroplast function in epidermal pavement cells, the potential role of SPL7-mediated copper homeostasis, and a putative Discussion: Together, this study provides the first single-cell-resolved transcriptional framework for
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