Evidence map›Paper›PMID 41800439›Full record

ArticleEvolutionary human sciences2026

Transmission of human handedness: a reanalysis.

Rony Karstadt, Chloe Shiff, Tomer Oron, Nadav Ben Nun, Yoav Ram

Abstract read
In one paragraph

Article in Evolutionary human sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rony KarstadtSchool of Zoology, Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.
Chloe ShiffInstitute for Computational and Mathematical Engineering, Stanford University, Stanford, CA, USA.
Tomer OronSchool of Zoology, Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.ORCID https://orcid.org/0009-0003-6719-9253
Nadav Ben NunSchool of Zoology, Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.
Yoav RamSchool of Zoology, Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.ORCID https://orcid.org/0000-0002-9653-4458

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human handedness results from the interplay of genetic and cultural influences. A gene-culture co-evolutionary model for handedness was introduced by Laland et al. (1995), and this study generalizes that model and the related analysis. We address ambiguities in the original methodology, particularly regarding maximum-likelihood estimation, and incorporate sex differences in cultural transmission. By fitting this extended framework to existing familial and twin datasets, we demonstrate that accounting for criterion shifts significantly improves model fit and parameter estimation accuracy. We find stronger maternal than paternal effects on handedness, with daughters exhibiting greater sensitivity to these effects than sons. We provide an open-source Python implementation of the model, which is a robust platform for comparing gene-culture models and applying them to diverse datasets.

Indexed as

cultural evolutiongene-culture co-evolutionhandednesshuman evolution

Identifiers

PMID41800439
PMCPMC12964082

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.