Evidence map›Paper›PMID 41801275›Full record

ArticleCurrent microbiology2026

In Vitro Characterization of Lactiplantibacillus Plantarum Strains: Probiotic Potential, Riboflavin Production, and Functional Properties.

Rania Rahmani, Amel Ait Meddour, Mohammed Benhoula, Samia Hamma-Faradji, Kahina Belbachir, Sylia Terki, Marco Calvigioni, Virginia Rossi, Diletta Mazzantini, Emilia Ghelardi and 2 more

Abstract read
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Article in Current microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rania RahmaniUniversité de Bejaia, Faculté des Sciences de la Nature et de la Vie, Laboratoire de Microbiologie Appliquée, Bejaia, 06000, Algeria. rania.rahmani@univ-bejaia.dz.ORCID http://orcid.org/0009-0000-3853-134X
Amel Ait MeddourUniversité de Bejaia, Faculté des Sciences de la Nature et de la Vie, Laboratoire de Microbiologie Appliquée, Bejaia, 06000, Algeria.
Mohammed BenhoulaCentre de Recherche en Technologies Agro-Alimentaires, Route de Targa Ouzemmour, Campus Universitaire, Bejaia, 06000, Algeria.
Samia Hamma-FaradjiUniversité de Bejaia, Faculté des Sciences de la Nature et de la Vie, Laboratoire de Microbiologie Appliquée, Bejaia, 06000, Algeria.
Kahina BelbachirUniversité de Bejaia, Faculté des Sciences de la Nature et de la Vie, Laboratoire de Microbiologie Appliquée, Bejaia, 06000, Algeria.
Sylia TerkiUniversité de Bejaia, Faculté des Sciences de la Nature et de la Vie, Laboratoire de Microbiologie Appliquée, Bejaia, 06000, Algeria.
Marco CalvigioniDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Virginia RossiDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Diletta MazzantiniDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Emilia GhelardiDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Mohamed SifourLaboratory of Molecular Toxicology, Faculty of Nature and Life Sciences, University of Jijel, Jijel, 18000, Algeria.
Houria Ouled-HaddarLaboratory of Molecular Toxicology, Faculty of Nature and Life Sciences, University of Jijel, Jijel, 18000, Algeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactiplantibacillus plantarum is commonly present in the gut microbiota of healthy individuals, as well as in a wide range of fermented foods and dairy products. Its well-documented probiotic potential, ability to produce bioactive compounds, and contribution to food preservation make it a promising candidate for functional food development. In this study, twenty-four lactic acid bacteria (LAB) isolates were obtained from various samples. The isolates were identified using Matrix-Assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS), and all were showed a high similarity to the species L. plantarum. Their probiotic properties were evaluated through a series of in vitro assays. Among these, fourteen isolates exhibited tolerance to gastrointestinal tract conditions, cell surface properties, and significant antimicrobial activity. Only two strains showed substantial adhesion to mucins. In vitro screening showed a considerable antioxidant activity and efficient cholesterol assimilation, as well as β-galactosidase and proteolytic activities. All the strains exhibited remarkable levels of riboflavin (vitamin B2) secretion, reaching concentrations of 1,646 ± 377.92 ng/mL. Most of the selected strains displayed safe antibiotic resistance profile and no pathogenic potential, suggesting that they are promising candidates for further investigation in human applications. Based on these findings, three L. plantarum strains were selected as promising candidates for in vivo applications in both food and human health. These strains exhibit potential not only as probiotics agents, but also as natural bioactive additives for nutritional fortification and food biopreservation.

Indexed as

Lactiplantibacillus plantarumProbioticsRiboflavinAntioxidantsBacterial AdhesionHumansSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationAntioxidantsRiboflavin

Identifiers

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.