Evidence map›Paper›PMID 41801296›Full record

ArticleJournal of natural medicines2026

Inhibitory effects of three genuine resin glycosides from Calystegia hederacea on in vitro porcine lipase assay and in silico docking simulation analysis.

Hirotaka Nishikawa, Masashi Hirano, Hideki Kinoshita, Kazunari Yoneda, Masateru Ono, Shin Yasuda

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of natural medicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hirotaka NishikawaGraduate School of Bioscience, Tokai University, Mashiki-Machi, Kamimashiki-Gun, Kumamoto, 861-2205, Japan.
Masashi HiranoGraduate School of Bioscience, Tokai University, Mashiki-Machi, Kamimashiki-Gun, Kumamoto, 861-2205, Japan.
Hideki KinoshitaGraduate School of Bioscience, Tokai University, Mashiki-Machi, Kamimashiki-Gun, Kumamoto, 861-2205, Japan.
Kazunari YonedaGraduate School of Bioscience, Tokai University, Mashiki-Machi, Kamimashiki-Gun, Kumamoto, 861-2205, Japan.
Masateru OnoGraduate School of Bioscience, Tokai University, Mashiki-Machi, Kamimashiki-Gun, Kumamoto, 861-2205, Japan.
Shin YasudaGraduate School of Bioscience, Tokai University, Mashiki-Machi, Kamimashiki-Gun, Kumamoto, 861-2205, Japan. shin.yasuda@tokai.ac.jp.ORCID http://orcid.org/0000-0002-1040-9243

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resin glycosides are characteristically present in Convolvulaceae plants. We recently demonstrated that three genuine resin glycosides, muricatins V, VI, and IX, from the seeds of Ipomoea muricata, inhibit lipase. This study investigated whether the resin glycoside fraction (CHRG Fr.) obtained from the whole plants of Calystegia hederacea and three resin glycosides, calyhedins II (1), III (2), and VIII (3), from the rhizomes of this plant, can inhibit porcine lipase in vitro. The results indicated the inhibitory effects of CHRG Fr. (IC

Indexed as

CalystegiaEnzyme InhibitorsGlycosidesLipaseResins, PlantAnimalsHumansMolecular Docking SimulationPlant ExtractsSwineEnzyme InhibitorsGlycosidesLipasePlant ExtractsResins, PlantCalyhedinCovolvulaceaeDocking simulationLipase inhibitorPancreatic lipase

Identifiers

PMID41801296
PMCPMC13186890

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.