Evidence map›Paper›PMID 41803229›Full record

ArticleScientific reports2026

Regulation of the AKT/P53 signaling pathway by translated control tumor protein inhibits apoptosis and promotes hyperplasia of the mammary glands.

Mu-Yuan Ma, Sheng Wang, Xue-Mei Jin, Yue Shen, Yi-Min Cai, Bin Yu, Huan-Huan Du, Liu Jia, Lei Ma, Jun-Fei Zhang

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mu-Yuan MaThe Second Department of Surgical Oncology, General Hospital of Ningxia Medical University, Yinchuan, 750000, Ningxia, China.
Sheng WangDepartment of Emergency Medical, General Hospital of Ningxia Medical University, 804 South Shengli Street, Xingqing District, Yinchuan City, 750000, Ningxia, China.
Xue-Mei JinDepartment of Pharmacy, Affiliated Hospital of Yanbian University, Yanji, 133000, Jilin Province, China.
Yue ShenDepartment of Emergency Medical, General Hospital of Ningxia Medical University, 804 South Shengli Street, Xingqing District, Yinchuan City, 750000, Ningxia, China.
Yi-Min CaiDepartment of Emergency Medical, General Hospital of Ningxia Medical University, 804 South Shengli Street, Xingqing District, Yinchuan City, 750000, Ningxia, China.
Bin YuObstetrics and Gynecology, Affiliated Hospital of Inner Mongolia Minzu University, Tongliao, Inner Mongolia Autonomous Region, 028000, China.
Huan-Huan DuPublic Health College of Inner Mongolia Minzu University, Tongliao, 028000, Inner Mongolia Autonomous Region, China.
Liu JiaMedical Experimental Center, General Hospital of Ningxia Medical University, 804 South Shengli Street, Xingqing District, Yinchuan City, 750000, Ningxia, China. liujia@nxmu.edu.cn.
Lei MaDepartment of Emergency Medical, General Hospital of Ningxia Medical University, 804 South Shengli Street, Xingqing District, Yinchuan City, 750000, Ningxia, China. 13895306161@163.com.
Jun-Fei ZhangDepartment of Emergency Medical, General Hospital of Ningxia Medical University, 804 South Shengli Street, Xingqing District, Yinchuan City, 750000, Ningxia, China. zhangjunfei007@126.com.

Funding

National Natural Science Foundation of China 82205116
6 · The paper itself

Abstract

This study aims to explore the mechanism by which the Translationally controlled tumor protein (TCTP) promotes hyperplasia of the mammary glands (HMG). In this study, the TCTP (Tpt1

Indexed as

ApoptosisBiomarkers, TumorMammary Glands, AnimalProto-Oncogene Proteins c-aktSignal TransductionTumor Suppressor Protein p53AnimalsFemaleHyperplasiaMiceMice, KnockoutTumor Protein, Translationally-Controlled 1Biomarkers, TumorProto-Oncogene Proteins c-aktTpt1 protein, mouseTrp53 protein, mouseTumor Protein, Translationally-Controlled 1Tumor Suppressor Protein p53Hyperplasia of the mammary glandsP53 proteinTranslationally controlled tumor protein

Identifiers

PMID41803229
PMCPMC13096157

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.