ArticleRenal failure2026
Impact of the drug-coated balloon-to-predilation balloon diameter ratio on restenosis risk in hemodialysis access: a study of nonlinear association.
Article in Renal failure, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundDrug-coated balloons (DCBs) improve the patency of hemodialysis access, yet restenosis rates remain substantial. This may be partly attributable to suboptimal balloon sizing. The relationship between the balloon diameter ratio (BDR; the ratio of DCB diameter to final predilation balloon diameter) and restenosis risk has not been clearly elucidated.
methodsThis retrospective study analyzed 123 patients who underwent DCB angioplasty for dysfunctional arteriovenous fistulas (AVF) or arteriovenous grafts (AVG). The primary endpoint was clinically driven target lesion restenosis within six months. Multivariable Cox regression and restricted cubic spline (RCS) analyses were used to evaluate the association between BDR and restenosis.
resultsThe six-month restenosis rate was 25.2%. BDR was an independent predictor of restenosis (
conclusionsBDR is a key, modifiable technical factor influencing patency after hemodialysis access intervention. Maintaining a BDR within the 0.9-1.1 range correlates with the lowest 6-month restenosis risk, yielding a clear and practical technical target for optimizing DCB angioplasty procedures.
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