ArticleBMC cardiovascular disorders2026
High bleeding risk and outcomes in left main percutaneous coronary intervention: prognostic value of the PRECISE-DAPT score.
Article in BMC cardiovascular disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe PRECISE-DAPT score is a standardized tool for assessing bleeding risk. However, its prognostic value in patients undergoing left main (LM) percutaneous coronary intervention (PCI) remains unclear. This study evaluated the association between high bleeding risk (HBR), defined by the PRECISE-DAPT score, and clinical outcomes following LM PCI.
methodsThis retrospective study analyzed consecutive patients undergoing LM PCI at a tertiary medical center. Patients were stratified into HBR (score ≥ 25) and non-HBR (score < 25) groups. The primary endpoint was major adverse cardiovascular and cerebrovascular events (MACCE), a composite of all-cause death, myocardial infarction, or stroke at one year.
resultsAmong 489 patients, 251 (51.3%) were classified as HBR. Compared with the non-HBR group, HBR patients exhibited significantly greater frailty, a higher burden of comorbidities, and more complex lesion characteristics. In multivariate Cox regression analysis, HBR was independently associated with an increased risk of MACCE (adjusted HR: 4.22; 95% CI: 2.03 to 8.77; P < 0.001) and bleeding events (adjusted HR: 5.11; 95% CI: 1.46 to 17.90; P = 0.01). Harrell’s C-index demonstrated good discrimination for MACCE (0.75; 95% CI: 0.70 to 0.79) and moderate discrimination for bleeding events (0.68; 95% CI: 0.57 to 0.79).
conclusionHBR, as determined by the PRECISE-DAPT score, is prevalent among patients undergoing LM PCI and associates with increased frailty, comorbidity burden, and adverse ischemic and bleeding outcomes. The PRECISE-DAPT score effectively stratifies systemic risk and supports its integration into clinical decision-making for this high-risk population.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.