Evidence map›Paper›PMID 41803808›Full record

Trial reportBMC psychiatry2026

Sleep, rest-activity rhythm, cognitive and emotional symptoms in adult ADHD: unraveling the links with an actimetry-based approach.

Amélia Walter, Émilie Martz, Luisa Weiner, Henri Comtet, Raphaëlle Glacet, Ülker Kilic-Huck, Patrice Bourgin, Carmen M Schröder, Sébastien Weibel

2 registry-linked trialsAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02858765 nacompletednot on this map

Influence of Light on Sleep, Awakening, Electroencephalogram (EEG) and Cognitive Performances, and Medical Technology Assessment for Registration and Long-term EEG Analysis

TypeinterventionalSponsorUniversity Hospital, Strasbourg, FranceRan2016 to 2019Enrolled92ConditionsHuman Sleep and ChronobiologyArmsApplication of white polychromatic light for 2h30 at different times of day
NCT03494478 naunknown statusnot on this map

Emotional Dysregulation and Cyclothymia in Adult Patients With ADHD: Cohort Follow-up of Patients in Two Referral Centers

TypeinterventionalSponsorUniversity Hospital, Strasbourg, FranceRan2019 to 2023Enrolled120ConditionsAdult ADHDArmsNeuropsychological testing, Actimetry, Self-questionnaires on emotional topics
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amélia WalterInstitute of Cellular and Integrative Neurosciences, CNRS UPR 3212, University of Strasbourg, Strasbourg, France. amelia-walter@outlook.fr.
Émilie MartzLaboratory of Psychology of Cognitions, University of Strasbourg, Strasbourg, France.
Luisa WeinerLaboratory of Psychology of Cognitions, University of Strasbourg, Strasbourg, France.
Henri ComtetInstitute of Cellular and Integrative Neurosciences, CNRS UPR 3212, University of Strasbourg, Strasbourg, France.
Raphaëlle GlacetInstitute of Cellular and Integrative Neurosciences, CNRS UPR 3212, University of Strasbourg, Strasbourg, France.
Ülker Kilic-HuckInstitute of Cellular and Integrative Neurosciences, CNRS UPR 3212, University of Strasbourg, Strasbourg, France.
Patrice BourginInstitute of Cellular and Integrative Neurosciences, CNRS UPR 3212, University of Strasbourg, Strasbourg, France.
Carmen M SchröderInstitute of Cellular and Integrative Neurosciences, CNRS UPR 3212, University of Strasbourg, Strasbourg, France.
Sébastien WeibelDepartment of Psychiatry, Strasbourg University Hospital, Strasbourg, France.

Funding

Adiral Association, Mundolsheim, France 9ADO/1089Eurometropole of Strasbourg LS 136213European Collectivity of Alsace - Grand Est Region 1182/15/C1
6 · The paper itself

Abstract

backgroundAttention Deficit Hyperactivity Disorder (ADHD) in adults is characterized by cognitive, behavioral and affective symptoms. Emotion dysregulation (ED), psychiatric comorbidities, and disturbances in sleep and circadian rhythms frequently co-occur with ADHD, yet their relationships have rarely been investigated using objective measures and are overlooked in therapeutic approaches. This study aimed to compare sleep and rest-activity rhythm parameters between adults with ADHD and control subjects and to examine their associations with cognitive and emotional symptoms in adults with ADHD.

methodsFifty-four adults with ADHD completed self-report questionnaires assessing inattention, hyperactivity/impulsivity, and emotional symptoms of ADHD, along with a neuropsychological evaluation of attentional and executive functions. Sleep patterns and rest-activity rhythm were monitored using actigraphy over a 10-days period and compared to data from 47 control participants without psychiatric or neurodevelopmental disorders, adjusting for age and sex. Relationships between ADHD symptoms, neuropsychological test results, sleep and rest-activity rhythm parameters were examined using correlation analyses.

resultsAdults with ADHD exhibited a more unstable and delayed rhythm compared to controls. Sleep and rest-activity rhythm disturbances were significantly associated with cognitive and behavioral symptoms, particularly hyperactivity. Longer sleep latency was associated with poorer selective attention, while shorter total sleep time was linked to deficits in inhibitory control. However, no significant associations were found between sleep, circadian rhythms, and ED symptoms and the majority of observed correlations were no longer significant after correction for multiple comparisons.

conclusionsThese findings highlight the intricate interplay between sleep and circadian rhythm disturbances and the core symptoms of ADHD, emphasizing the need to consider sleep and circadian rhythms interventions in the management of core ADHD symptoms in adults.

trial registrationThe study involving adults with ADHD, Emotional Dysregulation and Cyclothymia in Adult Patients With ADHD (EMO-TDA), was registered at ClinicalTrials.gov (Identifier: NCT03494478) on April 11, 2018. The study involving control participants, Influence of Light on Sleep, Awakening, Electroencephalogram (EEG) and Cognitive Performances, and Medical Technology Assessment for Registration and Long-term EEG Analysis (CHRONOSOMNO), was registered at ClinicalTrials.gov (Identifier: NCT02858765) on August 8, 2016.

Indexed as

Affective SymptomsAttention Deficit Disorder with HyperactivityCognitionEmotionsRestSleepSleep Wake DisordersActigraphyAdultAttentionCircadian RhythmExecutive FunctionFemaleHumansMaleMiddle AgedActigraphyAdult ADHDCognitive functionsEmotion dysregulationSleep

Identifiers

PMID41803808
PMCPMC13085561

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.