ArticleScience progress
A real-world retrospective cohort study comparing brand-name febuxostat (feburic) and generic febuxostat (feuri).
Article in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ObjectiveTo compare the effectiveness, safety, and cost outcomes of brand-name febuxostat (feburic) and generic febuxostat (feuri) in patients with hyperuricemia or gout in a real-world clinical setting.MethodsWe conducted a retrospective cohort study using electronic medical records from Taichung Veterans General Hospital between November 2021 and December 2023. Adult patients with hyperuricemia or gout who initiated febuxostat therapy and had no prior urate-lowering treatment in the preceding 3 months were included. Serum uric acid levels were assessed at baseline, 3 months, and the final follow-up. Propensity score matching (1:1) was applied to balance baseline demographic, clinical, laboratory, cardiovascular, and renal characteristics. Clinical outcomes, laboratory parameters, and medication costs were compared between groups.ResultsBoth feuri and feburic were associated with significant reductions in serum uric acid levels after 3 months of treatment. At the 3-month assessment, the mean serum uric acid level was modestly lower in the feuri group (5.41 ± 2.06 mg/dL) than in the feburic group (5.75 ± 2.12 mg/dL;
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