ArticleArchives of endocrinology and metabolism2026
MicroRNAs miR-29a-3p and miR-192-5p: promising urinary biomarkers for kidney function loss.
Article in Archives of endocrinology and metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Urinary Extracellular Vesicle-Derived miRNAs as Regulators and Biomarkers in Diabetic Kidney Disease.International journal of molecular sciences · 2026Review
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4 authors.
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Abstract
objectiveThis study aimed to evaluate the expression of miR-29a-3p and miR-192-5p in patients with type 1 diabetes mellitus (T1DM) with diabetic kidney disease (DKD) compared to those without DKD. SUBJECTS AND
methodsThis study included 29 patients with T1DM, comprising 13 without DKD (non-DKD group) and 16 with DKD, who were further subdivided into nine patients with moderate DKD and seven with severe DKD. MiR-29a-3p and miR-192-5p expression levels were measured in urine samples using qPCR and are presented as medians (25-75th percentiles).
resultsmiR-29a-3p levels were higher in patients with DKD compared to the non-DKD group [1.24 (0.97-1.74) versus 0.83 (0.72-0.99); P = 0.008]. Its expression showed a negative correlation with estimated glomerular filtration rate (eGFR) (P = 0.007) and a positive correlation with creatinine levels (P = 0.004). MiR-192-5p levels were higher in patients with moderate DKD compared to the non-DKD group [2.15 (1.45-4.21) versus vs. 1.42 (0.98-2.45); P = 0.015], showing a negative correlation with eGFR (P = 0.003) and a positive correlation with creatinine (P = 0.006).
conclusionThe differential expression of miR-29a-3p and miR-192-5p in DKD highlights their potential as promising biomarkers for this complication.
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