Evidence map›Paper›PMID 41805314›Full record

ArticleAnalytical chemistry2026

Robust Rapid Cellular Metabolite Sensing Using Benchtop NMR and SABRE-Hyperpolarized [1-

Joseph Gyesi, Patrick TomHon, Abubakar Abdurraheem, Anna Samoilenko, Sydney Scofield, Clementinah Oladun, Stephen McBride, Erica Curran, Megan Pike, Kamal Kadari and 9 more

Abstract read
In one paragraph

Article in Analytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. High-resolution microtesla in-situJournal of magnetic resonance (San Diego, Calif. : 1997) · 2026
    Article
  2. AutomatedAnalytical chemistry · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Joseph GyesiDepartment of Chemistry, Integrative Biosciences (Ibio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan 48202, United States.
Patrick TomHonDepartment of Chemistry, Integrative Biosciences (Ibio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan 48202, United States.ORCID 0000-0003-3202-9812
Abubakar AbdurraheemDepartment of Chemistry, Integrative Biosciences (Ibio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan 48202, United States.
Anna SamoilenkoDepartment of Chemistry, Integrative Biosciences (Ibio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan 48202, United States.
Sydney ScofieldBiological Sciences, Institute of Environmental Health Sciences, Wayne State University, Detroit, Michigan 48202, United States.
Clementinah OladunDepartment of Chemistry, Integrative Biosciences (Ibio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan 48202, United States.
Stephen McBrideDepartment of Chemistry, NC State University, Raleigh, North Carolina 27606, United States.
Erica CurranDepartment of Chemistry, NC State University, Raleigh, North Carolina 27606, United States.ORCID 0009-0005-1376-5541
Megan PikeDepartment of Chemistry, NC State University, Raleigh, North Carolina 27606, United States.
Kamal KadariDepartment of Chemistry, Integrative Biosciences (Ibio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan 48202, United States.
Sydney D WelchDepartment of Chemistry, Integrative Biosciences (Ibio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan 48202, United States.
Sam LipkaDepartment of Chemistry, Integrative Biosciences (Ibio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan 48202, United States.
Steven BalboaDepartment of Chemistry, Integrative Biosciences (Ibio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan 48202, United States.
Charlie FehlDepartment of Chemistry, Integrative Biosciences (Ibio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan 48202, United States.ORCID 0000-0001-6182-0879
Marianna SadagurskiBiological Sciences, Institute of Environmental Health Sciences, Wayne State University, Detroit, Michigan 48202, United States.
Jan-Bernd HövenerSection Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC) Department of Radiology and Neuroradiology, University Medical Center Kiel, Kiel University, Am Botanischen Garten 18, Kiel 24118, Germany.ORCID 0000-0001-7255-7252
Thomas TheisDepartment of Chemistry, NC State University, Raleigh, North Carolina 27606, United States.ORCID 0000-0001-6779-9978
Boyd M GoodsonSchool of Chemical & Biomolecular Sciences, Southern Illinois University, Carbondale, Illinois 62901, United States.ORCID 0000-0001-6079-5077
Eduard Y ChekmenevDepartment of Chemistry, Integrative Biosciences (Ibio), Karmanos Cancer Institute (KCI), Wayne State University, Detroit, Michigan 48202, United States.ORCID 0000-0002-8745-8801

Funding

PIGE: The Program Integrating Genomics and the EnvironmentT32ES036169 · NIEHS · WAYNE STATE UNIVERSITY · PI Wanqing Liu, Douglas M Ruden · 2025 to 2026
$560k
NIEHS NIH HHS T32 ES036169
6 · The paper itself

Abstract

Hyperpolarized NMR has emerged as a powerful analytical technique to significantly enhance targeted NMR signals, improving the sensitivity for investigations of unique chemical and biological dynamics. Here, we demonstrate the use of a hyperpolarization strategy based on Signal Amplification By Reversible Exchange (SABRE) to generate highly reproducible doses of a hyperpolarized [1-

Indexed as

Pyruvic AcidSaccharomyces cerevisiaeBicarbonatesCarbon IsotopesMagnetic Resonance SpectroscopyBicarbonatesCarbon-13Carbon IsotopesPyruvic Acid

Identifiers

PMID41805314
PMCPMC13019433

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.