ReviewArchives of microbiology2026
Sporobolomyces pararoseus: a versatile chassis for circular bioproduction of β-carotene, torulene, and torularhodin.
Review in Archives of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Recent advances in biomanufacturing have stimulated the exploration of microbial platforms for pigment production, offering alternatives to plant-derived and synthetic colorants. Among these biological solutions, microbial carotenoids, a group of naturally occurring pigments, have emerged as particularly valuable due to their vibrant red, orange, and yellow coloration coupled with demonstrated antioxidant capacity and health-promoting benefits. Sporobolomyces pararoseus, one of the most well-studied oleaginous red yeasts, exhibits a remarkable ability to simultaneously produce three commercially valuable carotenoids—β-carotene, torulene, and torularhodin—under scalable fermentation conditions, making it an attractive microbial platform for industrial biotechnology. This review summarizes current knowledge on S. pararoseus as a promising microbial cell factory for carotenoid production, emphasizing its distinctive biological characteristics and environmental adaptability, enzymatic pathways governing carotenoid synthesis, state-of-the-art biotechnological interventions to enhance productivity and recovery efficiency, and potential commercial applications across diverse biotechnology sectors. Current challenges in carotenogenic pathway optimization, genetic tool development, scale-up economics, and market regulatory construction are addressed alongside integrated solutions employing CRISPR-based genome editing techniques, multi-omics profiling approaches, circular bioeconomy strategies, and comprehensive safety evaluation procedures. Through synthesis of contemporary scientific understanding with innovative bioprocessing techniques, this review connects fundamental insights into S. pararoseus biology with actionable methodologies for commercial-scale implementation, and suggests that this yeast could serve as a microbial platform for sustainable production of β-carotene, torulene, and torularhodin to meet global market demands.
Indexed as
Identifiers
41805943What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.