Evidence map›Paper›PMID 41806345›Full record

ArticleBulletin of experimental biology and medicine2025

The Level of Ischemia-Modified Albumin in Healthy Individuals of Different Age Groups.

Yu O Teselkin, I V Babenkova, I V Tarasova, A A Kubrikova, I D Strazhesko, O N Tkacheva, A N Osipov

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Article in Bulletin of experimental biology and medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yu O TeselkinPirogov Russian National Research Medical University (Pirogov University), Ministry of Health of the Russian Federation, Moscow, Russia. teselkin-box@mail.ru.
I V BabenkovaPirogov Russian National Research Medical University (Pirogov University), Ministry of Health of the Russian Federation, Moscow, Russia.
I V TarasovaPirogov Russian National Research Medical University (Pirogov University), Ministry of Health of the Russian Federation, Moscow, Russia.
A A KubrikovaPirogov Russian National Research Medical University (Pirogov University), Ministry of Health of the Russian Federation, Moscow, Russia.
I D StrazheskoPirogov Russian National Research Medical University (Pirogov University), Ministry of Health of the Russian Federation, Moscow, Russia.
O N TkachevaPirogov Russian National Research Medical University (Pirogov University), Ministry of Health of the Russian Federation, Moscow, Russia.
A N OsipovPirogov Russian National Research Medical University (Pirogov University), Ministry of Health of the Russian Federation, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The serum levels of oxidative stress marker, ischemia-modified albumin (IMA) were studied in healthy young (18-49 years), middle-aged (51-68 years), elderly and older (73-99 years) people. The content of IMA was measured using albumin cobalt binding assay. In addition, the IMA/albumin ratio (IMAR) was calculated. The content of IMA was elevated in the elderly individuals in comparison with the other two age groups (p < 0.05). Similar changes were observed for IMAR (p < 0.01). A positive correlation was established between the levels of IMA, IMAR, and age in the total group of volunteers (r = 0.308, p < 0.05 and r = 0.412, p < 0.01, respectively). The results show that oxidative modification of serum albumin increases with age.

Indexed as

AgingSerum AlbuminSerum Albumin, HumanAdolescentAdultAgedAged, 80 and overAge FactorsBiomarkersCobaltFemaleHumansMaleMiddle AgedOxidative StressYoung AdultBiomarkersCobaltischemia-modified albuminSerum AlbuminSerum Albumin, HumanagingCo(II)-binding capacity of albuminischemia-modified albuminoxidative stressserum albumin

Identifiers

PMID41806345

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.