Evidence mapPaperPMID 41807803Full record

ReviewCellular and molecular life sciences : CMLS2026

Harnessing the power of the gut microbiome: a review of supplementation diagnosis and therapy for liver cirrhosis.

Yuanqing Zhu, Wenkang Gao, Mingjian Cheng, Xuyang Li, Kailin Cai, Liuying Chen, Huikuan Chu

Abstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuanqing Zhu *Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, Hubei Province, China.
Wenkang Gao *Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, Hubei Province, China.
Mingjian ChengDivision of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, Hubei Province, China.
Xuyang LiThe 1st Clinical School, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, Hubei Province, China.
Kailin CaiUnion Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Liuying ChenDepartment of Clinical Nutrition, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. jinniuzuo400@126.com.
Huikuan ChuDivision of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, Hubei Province, China. 2012xh0827@hust.edu.cn.ORCID http://orcid.org/0000-0001-5349-8429

Funding

Key Technologies Research and Development Program No. 2022YFA1305600National Natural Science Foundation of China No. 82000561National Natural Science Foundation of China No. 82170678National Natural Science Foundation of China No. 82400652National Natural Science Foundation of China No. 82470584Science Foundation of Union Hospital No. 2021xhyn005
6 · The paper itself

Abstract

Liver cirrhosis is an end-stage pathological process caused by various chronic liver diseases, whose incidence is increasing and represents a serious public health burden. The onset of liver cirrhosis is related to various factors such as alcohol, autoimmune, steatosis, and viral infections. Recent research suggests that the gut microbiota also participates in the progression of liver cirrhosis and that supplementation with probiotics improves the progression of liver diseases. We have reviewed the latest studies on the mutual influence between the gut microbiota (including bacteria, fungi and virus) and cirrhosis, and summarized the changes in the gut microbiota, the immune and metabolic mechanisms, and the application of gut microbiota in the clinical management, hoping to provide new strategies for the diagnosis and treatment of liver cirrhosis.

Indexed as

Gastrointestinal MicrobiomeLiver CirrhosisProbioticsAnimalsDietary SupplementsHumansGut-liver axisGut microbiotaLiver cirrhosisTreatment

Identifiers

PMID41807803
PMCPMC13013790

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.