SynthesisBMC musculoskeletal disorders2026
Comparison of conventional and minimally invasive approaches of primary total knee arthroplasty: a network meta-analysis of randomized controlled trials.
Synthesis in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
3 authors.
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Abstract
backgroundThe purpose of this study was to evaluate the efficacy of conventional and minimally invasive approaches to total knee arthroplasty (TKA) by comparing the pain score, range of motion (ROM), and adverse effects. It was hypothesized that minimally invasive approaches would lead to superior outcomes.
methodsRandomized control trials comparing various approaches to TKA were identified in various literature databases from conception through December 31, 2022. A network meta-analysis (NMA) of relevant literature was performed to investigate which approaches showed better outcomes. In total, 42 studies were included in this study.
resultsThe main finding of this NMA was that the minimally invasive midvastus (MMV) approach led to better outcomes in terms of pain score (with a surface under the cumulative ranking curve [SUCRA] value of 80.0 and a mean rank of 2.2). Also, the minimally invasive quadriceps-sparing (MQS) approach led to better outcomes in terms of ROM (with a SUCRA value of 90.0 and a mean rank of 1.6). However, the subvastus (SV) and quadriceps-splitting (Qsplitt) approaches led to better outcomes in terms of reduction in adverse effects (SV: SUCRA value of 80.0 and a mean rank of 2.4; Qsplitt: SUCRA value of 70.0 and a mean rank of 3.1).
conclusionAccording to this NMA, minimally invasive approaches of TKA led to better outcomes in terms of pain score and ROM, while conventional approaches of TKA led to better outcomes in terms of safety. Therefore, orthopedic surgeons should consider various factors when choosing the TKA approach.
trial registrationPROSPERO: CRD42024548966
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.