Evidence mapPaperPMID 41809153Full record

ArticleWorld journal of methodology2026

Association of neutrophil-lymphocyte ratio with all-cause and cardiovascular mortality in peritoneal dialysis patients: A systematic review and meta-analysis.

Nanush Damarlapally, Roopeessh Vempati, Denise Mourad, Srivatsa Surya Vasudevan, Gaurav Mathur, Afrasayab Khan, Prathibha Banda, Harshavardhan Polamarasetty, Shaylika Chauhan, Nirmala Manjappachar and 2 more

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Article in World journal of methodology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Nanush DamarlapallyDepartment of Health Sciences, Houston Community College-Coleman Campus, Houston, TX 77030, United States.
Roopeessh VempatiDepartment of Internal Medicine, Trinity Health Oakland Hospital, Pontiac, MI 48341, United States.
Denise MouradDepartment of Internal Medicine, Central Michigan University, Saginaw, MI 48602, United States.
Srivatsa Surya VasudevanDepartment of Otolarngology, Louisiana State University Health Sciences Center, Shreveport, LA 70112, United States.
Gaurav MathurDepartment of Internal Medicine, Connecticut Institute for Communities, Danbury, CT 06810, United States.
Afrasayab KhanDepartment of Internal Medicine, Central Michigan University, Saginaw, MI 48602, United States.
Prathibha BandaDepartment of Internal Medicine, Gandhi Medical College and Hospital, Secunderabad 500003, Telangāna, India.
Harshavardhan PolamarasettyDepartment of Biomedical Engineering, University of Houston, Houston, TX 77004, United States.
Shaylika ChauhanDepartment of Internal Medicine, Geisinger Health System, Wikes-Barre, PA 18707, United States. drshaylikachauhan@gmail.com.
Nirmala ManjappacharDepartment of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN 55905, United States.
Talha BhattiDepartment of Cardiology, Lower Bucks Hospital, Bristol, PA 19007, United States.
Rupak DesaiDepartment of Outcomes Research, Independent Researcher, Atlanta, GA 30079, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe neutrophil-to-lymphocyte ratio (NLR) is a novel inflammatory marker predicting cardiovascular mortality (CVM) and all-cause mortality (ACM).

aimTo investigate the association between the NLR and CVM and ACM in patients with peritoneal dialysis (PD).

methodsWe reviewed articles from PubMed, Google Scholar, and Scopus until May 2024 for the association of ACM and CVM in patients with NLR following PD. We used a fixed effects model and

resultsOut of 160 articles screened, seven studies from 2011 to 2024 with 4350 patients, a mean age of 49.9 years ± 15 years, and a median follow-up of 4 years were included. We found that higher NLR (> 3) was significantly associated with ACM [adjusted HR (aHR): 1.18, 95%CI: 1.03-1.36,

conclusionOur meta-analysis identifies a significant association between NLR (> 3) and ACM outcome, which can help prevent deaths in the elderly and optimize resource use. Caution is needed when predicting mortality in this group as age significantly confounds ACM in patients undergoing PD.

Indexed as

All-cause mortalityCardiac arrestCardiovascular mortalityChronic renal failureDialysisElderlyEnd stage renal diseaseMortalityNeutrophil-to-lymphocyte ratioPeritoneal dialysis

Identifiers

PMID41809153
PMCPMC12968771

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.