Evidence map›Paper›PMID 41809212›Full record

ReviewWorld journal of gastrointestinal pharmacology and therapeutics2026

Gut-brain axis and post-operative cognitive dysfunction: A multifactorial perspective on microbiota, inflammation, and cognitive health.

Rhythm Joshi, Nishkarsh Gupta, Anju Gupta, Puneet Khanna, Nishant Verma, Simran Kaur

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of gastrointestinal pharmacology and therapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rhythm JoshiDepartment of Anesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi 110029, Delhi, India.
Nishkarsh GuptaDepartment of Onco-Anesthesiology and Palliative Medicine, All India Institute of Medical Sciences, New Delhi 110029, Delhi, India.
Anju GuptaDepartment of Anesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi 110029, Delhi, India. dranjugupta09@gmail.com.
Puneet KhannaDepartment of Anesthesiology, All India Institute of Medical Sciences, New Delhi 110029, Delhi, India.
Nishant VermaDepartment of Microbiology, All India Institute of Medical Sciences, New Delhi 110029, Delhi, India.
Simran KaurDepartment of Physiology, All India Institute of Medical Sciences, New Delhi 110029, Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-operative cognitive dysfunction (POCD) is a common but often overlooked issue, especially in older adults after surgery. This review looks into how the gut and brain are connected-a relationship known as the gut-brain axis-and how tiny microbes living in our gut might influence our brain health during recovery. The gut microbiota helps produce important substances like short-chain fatty acids and neurotransmitters that play a key role in memory, mood, and brain function. Among these microbes,

Indexed as

Akkermansia muciniphilaCognitive outcomes after surgeryGut-brain axisGut dysbiosisGut microbiotaMicrobiota-based targeted therapyNeuroinflammationPost-operative cognitive dysfunctionProbiotic interventionShort-chain fatty acids

Identifiers

PMID41809212
PMCPMC12968641

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.